Laboratory of Neurogenetics - National Inst. of Aging - NIH
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GWAS-pipeline
GWAS-pipeline PublicThis is a general (somewhat comprehensive) description of the LNG GWAS pipeline which can be used to guide researchers on how-to run a GWAS.
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Discovery, validation, and in vitro modeling of glial states across human neurodegenerative diseases
neurogenetics/Glia_across_NDDs’s past year of commit activity - SAHAdata Public
neurogenetics/SAHAdata’s past year of commit activity - LRRK2_IFN_iMicroglia_Human_Mouse Public
This repository contains data and analysis related to the study of how IFN-γ-induced inflammation regulates the expression of the Parkinson’s disease-associated kinase LRRK2 across multiple experimental models. These include iPSC-derived microglia, human brain slices, and in vivo mouse experiments.
neurogenetics/LRRK2_IFN_iMicroglia_Human_Mouse’s past year of commit activity - Lrrk2_LPS_scRNAseq Public
scRNA-seq analysis of striatum and midbrain cells from mice harboring R1441C or G2019S mutations, injected instrastriatally with PBS or LPS.
neurogenetics/Lrrk2_LPS_scRNAseq’s past year of commit activity - Xenium_Line61_spatial Public
neurogenetics/Xenium_Line61_spatial’s past year of commit activity
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