Regularized scVI for complex multiome single-cell/nucleus datasets: ambient RNA correction, dispersion prior, and batch-free decoder act as structural inductive biases that make large-architecture VAEs well-behaved without per-dataset tuning.
rna-seq pytorch dispersion regularization single-cell variational-autoencoder batch-correction ambient-rna scverse scvi cell2location single-nucleus
-
Updated
Mar 24, 2026 - Python