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@aleixpuigb aleixpuigb commented Dec 17, 2025

Fixes #3640
The eyelid is a composite anatomical structure that is not solely composed by skin. This PR updates the definition to reflect this and provides a dbxref:

A movable anterior covering of the eye composed of skin, muscle, dense connective tissue (tarsal plate) with embedded meibomian glands, and palpebral conjunctiva; functions to protect the eyeball, distribute the tear film, and maintain the eyelash margin. (PMID:29493929)

Fixes #3640 to correctly classify eyelid as a facial skin
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#gogoeditdiff

@aleixpuigb aleixpuigb changed the title Fixes #3640 to correctly classify eyelid as a facial skin Fixes #3640 to correctly classify eyelid as a 'skin of face' Dec 17, 2025
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Pull request overview

This PR attempts to fix issue #3640 by reclassifying the eyelid from "organ part" to "zone of skin". However, this change is semantically incorrect based on the anatomical composition of the eyelid and established ontology patterns.

Key Changes:

  • Changed the parent classification of eyelid (UBERON:0001711) from "organ part" (UBERON:0000064) to "zone of skin" (UBERON:0000014)

@aleixpuigb aleixpuigb changed the title Fixes #3640 to correctly classify eyelid as a 'skin of face' Fixes #3640 Update eyelid textual definition Dec 17, 2025
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Pull request overview

Copilot reviewed 1 out of 1 changed files in this pull request and generated no new comments.

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Copilot AI commented Jan 5, 2026

@dosumis I've opened a new pull request, #3643, to work on those changes. Once the pull request is ready, I'll request review from you.

Copilot AI added a commit that referenced this pull request Jan 5, 2026
- Changed is_a from organ part to external soft tissue zone (UBERON:0034929)
- Added has_part relationships for skin of eyelid and palpebral conjunctiva
- Follows pattern established by prepuce for multi-tissue surface structures
- Addresses feedback on PR #3641 about semantic classification

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Co-authored-by: dosumis <112839+dosumis@users.noreply.github.com>
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dosumis commented Jan 5, 2026

Looks great but we need to be careful about species specificity - see https://chatgpt.com/share/695be87e-5674-800f-8d22-1862ee3c772e

Maybe have a general term eyelid for vertebrates and keep this one for mammals, but indicate parenthetically bits that only apply to humans or primates.

Potential general term:
“A movable or semi-movable ocular covering that protects the eye and contributes to surface maintenance; structure and composition vary widely among vertebrate species.”

Edits to this term def:

A movable anterior covering of the eye composed of skin, muscle, dense connective tissue (tarsal plate in humans, primates) with embedded meibomian glands, and palpebral conjunctiva; functions to protect the eyeball, distribute the tear film, and maintain the eyelash margin where this is present (humans, primates and some carnivores).

  • add (Mammal) to end of name and subClassOf: in_taxon mammal

@aleixpuigb aleixpuigb requested a review from dosumis January 20, 2026 16:27
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I have made the term general for any species with eyelids. I am not sure if we need a specific term for mammals/humans.

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aleixpuigb commented Jan 20, 2026

We need to merge #3652 first to solve the problems.

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Eyelid as part of skin of head

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