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Unified Python toolkit for genome editing (CRISPR/prime/base): design, off-target scoring, QC, and analysis.

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Geneops

Unified Python toolkit for genome editing workflows: CRISPR, base editing, and prime editing. Design guides, score off-targets, model edit outcomes, and analyze results through a consistent.


What is Geneops?

Geneops is an open-source Python library that provides shared core primitives and pipelines for genome editing tasks, including:

  • CRISPR guide RNA design
  • Off-target discovery and scoring
  • Nuclease and PAM constraint modeling
  • Edit outcome prediction (indels, base edits, prime edits)
  • QC and downstream analysis

Install

# Create virtual env
python -m venv venv
source venv/bin/activate

# Install geneops
pip install -e .

Map

Overview of the current geneops architecture and how its core modules connect from guide design and nuclease modeling through edit outcome prediction and analysis. etc...

Map


Contributions are welcome! Please open issues or pull requests on the GitHub repository.

Contact: ntfargo@proton.me

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Unified Python toolkit for genome editing (CRISPR/prime/base): design, off-target scoring, QC, and analysis.

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