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14 changes: 14 additions & 0 deletions references.bib
Original file line number Diff line number Diff line change
Expand Up @@ -25,6 +25,20 @@ @article{cai_2016_shared
year = {2016}
}

@article{guo_2023_miniscopelfov,
abstract = {Imaging large-population, single-cell fluorescent dynamics in freely behaving animals larger than mice remains a key endeavor of neuroscience. We present a large-field-of-view open-source miniature microscope (MiniLFOV) designed for large-scale (3.6 mm × 2.7 mm), cellular resolution neural imaging in freely behaving rats. It has an electrically adjustable working distance of up to 3.5 mm ± 100 μm, incorporates an absolute head orientation sensor, and weighs only 13.9 g. The MiniLFOV is capable of both deep brain and cortical imaging and has been validated in freely behaving rats by simultaneously imaging >1000 GCaMP7s-expressing neurons in the hippocampal CA1 layer and in head-fixed mice by simultaneously imaging ~2000 neurons in the dorsal cortex through a cranial window. The MiniLFOV also supports optional wire-free operation using a novel, wire-free data acquisition expansion board. We expect that this new open-source implementation of the UCLA Miniscope platform will enable researchers to address novel hypotheses concerning brain function in freely behaving animals. A large field of view open-source miniature microscope is capable of imaging large populations of neurons in rats and mice.},
author = {Changliang Guo and Garrett J. Blair and Megha Sehgal and Federico N. Sangiuliano Jimka and Arash Bellafard and Alcino J. Silva and Peyman Golshani and Michele A. Basso and Hugh Tad Blair and Daniel Aharoni },
doi = {10.1126/sciadv.adg3918},
eprint = {https://www.science.org/doi/pdf/10.1126/sciadv.adg3918},
journal = {Science Advances},
number = {16},
pages = {eadg3918},
title = {Miniscope-LFOV: A large-field-of-view, single-cell-resolution, miniature microscope for wired and wire-free imaging of neural dynamics in freely behaving animals},
url = {https://www.science.org/doi/abs/10.1126/sciadv.adg3918},
volume = {9},
year = {2023}
}

@article{zhao_2025_minixl,
abstract = {Capturing the intricate dynamics of neural activity in freely behaving animals is essential for understanding the neural mechanisms underpinning specific behaviors. Miniaturized microscopy enables investigators to track population activity at the cellular level, but the field of view (FOV) of these microscopes has often been limited and do not support multi-brain region imaging. To fill this technological gap, we have developed the eXtra Large FOV Miniscope (MiniXL) for mice, a 3.5-gram miniaturized microscope with an FOV measuring 3.5 mm in diameter. We demonstrate the capabilities of the MiniXL through large-scale neuronal population records in hippocampal dorsal CA1. We also demonstrate simultaneous multi-brain region imaging across bilateral medial prefrontal cortex (mPFC) and mPFC and nucleus accumbens (NAc) during complex social behavior and stably track cells across multiple days. As with all microscopes in the UCLA Miniscope ecosystem, the MiniXL is fully open-source and designed to be shared with the neuroscience community to lower the barriers for adoption of this technology. MiniXL expands open-source neural imaging in freely behaving mice, enabling large-scale, multi-region recordings.},
author = {Pingping Zhao and Changliang Guo and Mian Xie and Liangyi Chen and Peyman Golshani and Daniel Aharoni },
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