feat: implement variant association analysis#1272
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31puneet wants to merge 5 commits intomalariagen:masterfrom
Open
feat: implement variant association analysis#127231puneet wants to merge 5 commits intomalariagen:masterfrom
31puneet wants to merge 5 commits intomalariagen:masterfrom
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Hi @jonbrenas PTAL, meanwhile when you get time see #1051 |
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Closes #685
Adds
variant_association()performs Fisher's Exact Test between a specific SNP and resistance phenotype. Usesphenotypes_with_snps()internally, filters missing data, and returns odds ratio + p-value.How it works
phenotypes_with_snps()for a single coordinate (not the whole chromosome)scipy.stats.fisher_exact()and returns odds ratio + p-value