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Computational Biology Field Guide

An interactive reference guide to landmark papers, assays, and tools in computational biology and genomics since 2010. 179 curated entries spanning 23 domains, with pros/cons, technical details, field impact ratings, and PubMed links.

View the guide

Domains covered

sequencing · crispr · ml/ai · single-cell · immunology · epigenomics · drug discovery · spatial · tools/infra · gene editing · clinical genomics · delivery · population genomics · proteomics · RNA biology · foundation models · cancer genomics · protein folding · metagenomics · validated targets · drug modalities · causal inference · visualization

Features

  • Carousel layout — browse entries with keyboard arrows or swipe; center card is expanded
  • Filter by domain — pill buttons to narrow by category
  • Sort — by year (newest/oldest) or field impact score
  • Full-text search — searches titles, authors, summaries, and technical details
  • Read tracking — mark papers as read; filter to unread only; progress persists in the URL hash
  • Abbreviation tooltips — ~150 field-specific terms auto-linked with hover definitions
  • PubMed links — 137 entries link directly to their PubMed record for reference verification

Technical details

Zero dependencies, no build step. The entire app is a single index.html file (~3,952 lines) with embedded CSS and vanilla ES6+ JavaScript.

# Open directly
open index.html

# Or serve locally
python3 -m http.server 8000

Adding entries

Each entry in the DATA array follows this schema:

{
  id,           // unique integer
  year,         // publication year
  cats,         // array of category keys (see catLabels in source)
  impact,       // field impact score 1–5
  title,
  authors,
  journal,
  summary,      // 2–3 sentence overview
  pros,         // string array
  cons,         // string array
  details,      // technical deep dive
  url,
  pmid          // PubMed ID (optional; omit for preprints/tools without a canonical paper)
}

Use the /add-paper slash command in Claude Code for guided entry creation.

License

MIT

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A reading list that summarizes big papers since 2010

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