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Jakeelamb/README.md

Hi, I'm Jake 🦎

Comp Bio enthusiest

Bash Rust Python R

Academic research 🧬

Published and in-progress work from academia

Developments and Research🧩

Dino-tools

  • dino-seq
  • dino-quant
  • orbweaver - Compact grammar-derived motif graphs from genomic FASTA; cross-species comparison with bounded memory.
  • Raptor - Parallel graph-based RNA-seq assembler (k-mer extension, isoform graphs, optional GPU, HPC workflows).
  • motif_graph_explore - Genomic motif complexity via assembly-theory-style analysis. assemblers & motif graphs
  • hox-core - Workspace crates (hox-parse, hox-common, hox-graph, hox-align, hox-olap) for mmap I/O, FM/minimizer indexes, alignment benches, and Arrow/Parquet-oriented outputs.
  • genome-assembler-graph - Interactive map of modern assembly tools, inputs, outputs, and metrics.

Terminal & HPC utilities 🌿

TUI/CLI tools

  • **opengenome
  • BioDex - Terminal species atlas — taxonomy browser, cached research notebook, genome-stat lookup.
  • bio-terminal - DNA/RNA matrix rain and codon-aware helices (cargo install bio-terminal). * this one got its name changed to dino -dna
  • SWATCH - Slurm job monitor — real-time status, SSH auth, dark-theme GUI (pip install swatch-slurm).
  • bioutil - Workstation bootstrap for fresh Linux installs (conda, tools, paths).

Sequencing pipelines 🌾

  • nf_denovo_transcriptome - Sample sheet → QC → merge → normalize → rnaSPAdes/Trinity → BUSCO.
  • nf_BFFcent - Population genomics: read groups → alignment → GVCF → joint calling → PCA.
  • Repeatome_builder - Repeat-library assembly for non-model organisms.
    • add the nextflow pipelines here from opengenome as seperate pipelines and repos

Microscopy & labeling 🔬

Rust ports — legacy tools, measured rewrites 🦀

Agentic attempts at ports

  • spades-rs - SPAdes 4.2.0 rewrite workspace with upstream oracles and staged lane promotion.
  • hifiasm-rs - hifiasm / hifiasm-UL stage benchmarks before custom assembler code.
  • bowtie2-rs - Bowtie2 port workspace — lane-by-lane parity before aligner/index core.
  • bbnorm-rs - BBTools BBNorm-style read-depth normalization.
  • bio_format_speed - Reproducible checks for biological file-format overhead.

Misc

GitHub activity 🌱

GitHub Contribution Graph

Connect 🌲

GitHub Email


Popular repositories Loading

  1. BioDex BioDex Public

    Animal stat TUI widget

    Rust 2

  2. Mobile_DNA_Sim Mobile_DNA_Sim Public

    Makefile 1

  3. orbweaver orbweaver Public

    Grammar-derived motif graphs from genomic FASTA

    Rust 1

  4. opengenome opengenome Public

    Terminal utility for genomics workflows

    Shell 1

  5. Split-MultiFasta-Sequence Split-MultiFasta-Sequence Public

  6. Heat_shock_protein_selection_analysis Heat_shock_protein_selection_analysis Public

    Master's research: heat-shock protein orthogroup selection across fish

    Jupyter Notebook