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Preserving tissue structure through density-based spatial analysis with scider

Overview

This repository contains the code to reproduce the analysis in:

Li M*, Liu N*, Nguyen QH, Chen Y (2025). Preserving tissue structure through density-based spatial analysis with scider. bioRxiv https://doi.org/10.1101/2025.09.11.675745.

Example datasets

Xenium

The Xenium data is available as GEO series GSE243168.

The Cell type annotation is obtained from 10x Genomics.

The code for generating the figures in the paper is in Xenium.

Visium HD

The Visium HD data is available at the 10x Genomics

The code for generating the figures in the paper is in visiumHD.

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Code used in the scider manuscript

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