Simulation Model for Toxoplasma-infected Dendritic Cell Migration

A 2-dimensional simulation model for the Toxoplasma-infected dendritic cell migration in a straight channel to study the host-parasite intracellular positioning. This repository includes:

1. The LAMMPS software with a customized package for the simulation model.
2. Example results of simulations and videos. Detailed instructions for running the simulation can be found in ./LAMMPS/src/MYFIX/ReadMe.txt.

Reference:

Hijacked Immune Cells Traverse Microenvironmental Barriers by Positioning and Pushing their Intracellular Parasite Cargo Mauricio J.A. Ruiz-Fernandez, Jianfei Jiang, Armina Mortazavi, Bingzhi Wang, Artur Kuznetcov, Jack Merrin, Markus Meissner, Javier Periz, Benedikt Sabass, Jörg Renkawitz bioRxiv 2024.05.03.592378; doi: https://doi.org/10.1101/2024.05.03.592378