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I'm trying to estimate a subject's Age using the Clock_Horvath353.rds and Clock_Hannum.rds. I have downloaded the two rds files and attempted to load them into R using readRDS(), but it errors with "Error in readRDS("Clock_Horvath353.rds") : unknown input format". I am trying to follow the scripts provided in the Help files, but they skip this step:
``betas <- sesameDataGet('HM450.1.TCGA.PAAD')$betas
Not run:
download age models from
https://github.com/zhou-lab/InfiniumAnnotationV1/tree/main/Anno
e.g., Anno/HM450/Clock_Horvath353.rds
predictAge(betas, model)``
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