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# This CITATION.cff file was generated with cffinit.
# Visit https://bit.ly/cffinit to generate yours today!
cff-version: 1.2.0
title: ' A toolbox of machine learning software to support microbiome analysis '
message: >-
If you use this dataset, please cite it using the metadata
from this file.
type: dataset
authors:
- given-names: Laura J.
family-names: Marcos Zambrano
- given-names: Burcu
family-names: Bakir-Gungor
- given-names: Marcus
family-names: Frohme
- given-names: Kanita
family-names: Karaduzovic-Hadziabdic
- given-names: Thomas
family-names: Klammsteiner
- given-names: Eliana
family-names: Ibrahimi
- given-names: Leo
family-names: Lahti
- given-names: Tatjana
family-names: Loncar-Turukalo
- given-names: Xhilda
family-names: Dhamo
- given-names: Andrea
family-names: Simeon
- given-names: Alina
family-names: Nechyporenko
- given-names: Gianvito
family-names: Pio
- given-names: Piotr
family-names: Przymus
- given-names: Alexa
family-names: Sampri
- given-names: Vladimir T.
family-names: Trajkovik
- given-names: Oliver
family-names: Aasmets
- given-names: Ricardo
family-names: Araujo
- given-names: Ioannis
family-names: Anagnostopoulos
- given-names: Onder
family-names: Aydemir
- given-names: Magali
family-names: Berland
- given-names: María
family-names: de la Luz Calle
- given-names: Michelangelo
family-names: Ceci
- given-names: Hatice
family-names: Duman
- given-names: Aycan
family-names: Gundogdu
- given-names: Aki S.
family-names: Havulinna
- given-names: Kardohk H.
family-names: Kaka Bra
- given-names: Eglantina
family-names: Kalluci
- given-names: Sercan
family-names: Karav
- given-names: Daniel
family-names: Lode
- given-names: Marta B.
family-names: Lopes
- given-names: Patrick
family-names: May
- given-names: Bram
family-names: Nap
- given-names: Miroslava
family-names: Nedyalkova
- given-names: Ines
family-names: Paciencia
- given-names: Lejla
family-names: Pasic
- given-names: Mertixell
family-names: Pujolassos
- given-names: Rajesh
family-names: Shigdel
- given-names: Antonio
family-names: Susin
- given-names: Ines
family-names: Thiele
- given-names: Ciprian-Octavian
family-names: Truica
- given-names: Paul
family-names: Wilmes
- given-names: Ercüment
family-names: Yilmaz
- given-names: Malik
family-names: Yousef
- given-names: Marcus J.
family-names: Claesson
- given-names: Jaak
family-names: Truu
- given-names: Enrique
family-names: Carrillo de Santa Pau
identifiers:
- type: doi
value: 10.3389/fmicb.2023.1250806
repository-code: 'https://github.com/tklammsteiner/machine-learning-toolbox'
url: 'https://tklammsteiner.github.io/machine-learning-toolbox/'
abstract: >-
The human microbiome has become an area of intense
research due to its potential impact on human health.
However, the analysis and interpretation of this data have
proven to be challenging due to its complexity and high
dimensionality. Machine learning (ML) algorithms can
process vast amounts of data to uncover informative
patterns and relationships within the data, even with
limited prior knowledge. Therefore, there has been a rapid
growth in the development of software specifically
designed for the analysis and interpretation of microbiome
data using ML techniques. These software incorporate a
wide range of ML algorithms for clustering,
classification, regression, or feature selection, to
identify microbial patterns and relationships within the
data and generate predictive models. This rapid
development with a constant need for new developments and
integration of new features require efforts into compile,
catalog and classify these tools to create infrastructures
and services with easy, transparent, and trustable
standards. Here we review the state-of-the-art for ML
tools applied in human microbiome studies, performed as
part of the COST Action ML4Microbiome activities. This
scoping review focuses on ML based software and framework
resources currently available for the analysis of
microbiome data in humans. The aim is to support
microbiologists and biomedical scientists to go deeper
into specialized resources that integrate ML techniques
and facilitate future benchmarking to create standards for
the analysis of microbiome data. The software resources
are organized based on the type of analysis they were
developed for and the ML techniques they implement. A
description of each software with examples of usage is
provided including comments about pitfalls and lacks in
the usage of software based on ML methods in relation to
microbiome data that need to be considered by developers
and users. This review represents an extensive compilation
to date, offering valuable insights and guidance for
researchers interested in leveraging ML approaches for
microbiome analysis.
keywords:
- microbiome
- machine learning
- feature generation
- software
- feature analysis
- data integration
- microbial gene prediction
- microbial metabolic modeling