diff --git a/CPU_Mac_Requirements.txt b/CPU_Mac_Requirements.txt
index 2b3f3d1..3ba7ffd 100644
--- a/CPU_Mac_Requirements.txt
+++ b/CPU_Mac_Requirements.txt
@@ -124,7 +124,7 @@ traits==5.1.1
 wcwidth==0.1.7
 webencodings==0.5.1
 werkzeug==0.15.4
-wheel==0.33.4
+wheel==0.38.1
 widgetsnbextension==3.4.2
 wrapt==1.11.2
 xz==5.2.4