diff --git a/compiler/rustc_codegen_llvm/src/llvm_util.rs b/compiler/rustc_codegen_llvm/src/llvm_util.rs
index 73b7f699b606d..ee09a5258baf3 100644
--- a/compiler/rustc_codegen_llvm/src/llvm_util.rs
+++ b/compiler/rustc_codegen_llvm/src/llvm_util.rs
@@ -303,6 +303,11 @@ pub(crate) fn to_llvm_features<'a>(sess: &Session, s: &'a str) -> Option<LLVMFea
                 s => Some(LLVMFeature::new(s)),
             }
         }
+        Arch::Nvptx64 => match s {
+            "sm_88" | "ptx90" if major < 22 => None,
+            s if s.starts_with("sm_110") && major < 22 => None,
+            s => Some(LLVMFeature::new(s)),
+        },
         _ => Some(LLVMFeature::new(s)),
     }
 }
diff --git a/compiler/rustc_codegen_ssa/src/target_features.rs b/compiler/rustc_codegen_ssa/src/target_features.rs
index 3c771f0eb7ec4..d42823255028e 100644
--- a/compiler/rustc_codegen_ssa/src/target_features.rs
+++ b/compiler/rustc_codegen_ssa/src/target_features.rs
@@ -418,15 +418,43 @@ pub fn target_spec_to_backend_features<'a>(
 ) {
     let mut rust_features = vec![];
 
-    // This check handles SM versions that defaults (by LLVM) to unsupported (by Rust) PTX ISA versions.
-    // sm_70, sm_72 and sm_75 defaults to PTX ISA versions with major version 6, while sm_80 default to 7.0
-    if sess.target.arch == Arch::Nvptx64
-        && matches!(
-            sess.opts.cg.target_cpu.as_deref(),
-            None | Some("sm_70") | Some("sm_72") | Some("sm_75")
-        )
-    {
-        rust_features.push((true, "ptx70"));
+    if sess.target.arch == Arch::Nvptx64 {
+        // Starting with LLVM 22, the NVPTX backend still infers the minimum
+        // required PTX version from the selected CPU when none is selected
+        // explicitly, but no longer reflects that in the enabled subtarget
+        // features. If a PTX version below the required minimum is selected
+        // explicitly, LLVM errors.
+        // To keep cfg evaluation consistent and avoid LLVM errors, always
+        // select an explicit PTX version: whichever is higher between
+        //  - Rust's minimum required PTX version, and
+        //  - the CPU's minimum required PTX version.
+        let min_ptx = match sess.opts.cg.target_cpu.as_deref() {
+            Some("sm_86") => "ptx71",
+            Some("sm_87") => "ptx74",
+            Some("sm_88") => "ptx90",
+            Some("sm_90") => "ptx78",
+            Some("sm_90a") => "ptx80",
+            Some("sm_100") => "ptx86",
+            Some("sm_100f") => "ptx88",
+            Some("sm_100a") => "ptx86",
+            Some("sm_101") => "ptx86",
+            Some("sm_101f") => "ptx88",
+            Some("sm_101a") => "ptx86",
+            Some("sm_103") => "ptx88",
+            Some("sm_103f") => "ptx88",
+            Some("sm_103a") => "ptx88",
+            Some("sm_110") => "ptx90",
+            Some("sm_110f") => "ptx90",
+            Some("sm_110a") => "ptx90",
+            Some("sm_120") => "ptx87",
+            Some("sm_120f") => "ptx88",
+            Some("sm_120a") => "ptx87",
+            Some("sm_121") => "ptx88",
+            Some("sm_121f") => "ptx88",
+            Some("sm_121a") => "ptx88",
+            _ => "ptx70",
+        };
+        rust_features.push((true, min_ptx));
     }
 
     // Compute implied features
diff --git a/compiler/rustc_target/src/target_features.rs b/compiler/rustc_target/src/target_features.rs
index 70e45c9684264..1314128df82d0 100644
--- a/compiler/rustc_target/src/target_features.rs
+++ b/compiler/rustc_target/src/target_features.rs
@@ -606,25 +606,62 @@ const MIPS_FEATURES: &[(&str, Stability, ImpliedFeatures)] = &[
 
 const NVPTX_FEATURES: &[(&str, Stability, ImpliedFeatures)] = &[
     // tidy-alphabetical-start
+    ("sm_20", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_21", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_30", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_32", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_35", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_37", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_50", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_52", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_53", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_60", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_61", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
+    ("sm_62", Forbidden { reason: "unsupported compute capability", hard_error: true }, &[]),
     ("sm_70", Unstable(sym::nvptx_target_feature), &[]),
     ("sm_72", Unstable(sym::nvptx_target_feature), &["sm_70"]),
     ("sm_75", Unstable(sym::nvptx_target_feature), &["sm_72"]),
     ("sm_80", Unstable(sym::nvptx_target_feature), &["sm_75"]),
     ("sm_86", Unstable(sym::nvptx_target_feature), &["sm_80"]),
     ("sm_87", Unstable(sym::nvptx_target_feature), &["sm_86"]),
-    ("sm_89", Unstable(sym::nvptx_target_feature), &["sm_87"]),
+    ("sm_88", Unstable(sym::nvptx_target_feature), &["sm_87"]),
+    ("sm_89", Unstable(sym::nvptx_target_feature), &["sm_88"]),
     ("sm_90", Unstable(sym::nvptx_target_feature), &["sm_89"]),
     ("sm_90a", Unstable(sym::nvptx_target_feature), &["sm_90"]),
     // tidy-alphabetical-end
     // tidy-alphabetical-start
     ("sm_100", Unstable(sym::nvptx_target_feature), &["sm_90"]),
-    ("sm_100a", Unstable(sym::nvptx_target_feature), &["sm_100"]),
+    ("sm_100a", Unstable(sym::nvptx_target_feature), &["sm_100f"]),
+    ("sm_100f", Unstable(sym::nvptx_target_feature), &["sm_100"]),
     ("sm_101", Unstable(sym::nvptx_target_feature), &["sm_100"]),
-    ("sm_101a", Unstable(sym::nvptx_target_feature), &["sm_101"]),
-    ("sm_120", Unstable(sym::nvptx_target_feature), &["sm_101"]),
-    ("sm_120a", Unstable(sym::nvptx_target_feature), &["sm_120"]),
+    ("sm_101a", Unstable(sym::nvptx_target_feature), &["sm_101f"]),
+    ("sm_101f", Unstable(sym::nvptx_target_feature), &["sm_101"]),
+    ("sm_103", Unstable(sym::nvptx_target_feature), &["sm_100"]),
+    ("sm_103a", Unstable(sym::nvptx_target_feature), &["sm_103f"]),
+    ("sm_103f", Unstable(sym::nvptx_target_feature), &["sm_103", "sm_100f"]),
+    ("sm_110", Unstable(sym::nvptx_target_feature), &["sm_103"]),
+    ("sm_110a", Unstable(sym::nvptx_target_feature), &["sm_110f"]),
+    ("sm_110f", Unstable(sym::nvptx_target_feature), &["sm_110"]),
+    ("sm_120", Unstable(sym::nvptx_target_feature), &["sm_110"]),
+    ("sm_120a", Unstable(sym::nvptx_target_feature), &["sm_120f"]),
+    ("sm_120f", Unstable(sym::nvptx_target_feature), &["sm_120"]),
+    ("sm_121", Unstable(sym::nvptx_target_feature), &["sm_120"]),
+    ("sm_121a", Unstable(sym::nvptx_target_feature), &["sm_121f"]),
+    ("sm_121f", Unstable(sym::nvptx_target_feature), &["sm_121", "sm_120f"]),
     // tidy-alphabetical-end
     // tidy-alphabetical-start
+    ("ptx32", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx40", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx41", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx42", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx43", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx50", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx60", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx61", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx62", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx63", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx64", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
+    ("ptx65", Forbidden { reason: "unsupported PTX version", hard_error: true }, &[]),
     ("ptx70", Unstable(sym::nvptx_target_feature), &[]),
     ("ptx71", Unstable(sym::nvptx_target_feature), &["ptx70"]),
     ("ptx72", Unstable(sym::nvptx_target_feature), &["ptx71"]),
@@ -642,6 +679,8 @@ const NVPTX_FEATURES: &[(&str, Stability, ImpliedFeatures)] = &[
     ("ptx85", Unstable(sym::nvptx_target_feature), &["ptx84"]),
     ("ptx86", Unstable(sym::nvptx_target_feature), &["ptx85"]),
     ("ptx87", Unstable(sym::nvptx_target_feature), &["ptx86"]),
+    ("ptx88", Unstable(sym::nvptx_target_feature), &["ptx87"]),
+    ("ptx90", Unstable(sym::nvptx_target_feature), &["ptx88"]),
     // tidy-alphabetical-end
 ];
 
diff --git a/tests/ui/check-cfg/target_feature.stderr b/tests/ui/check-cfg/target_feature.stderr
index bcc3abf4ff267..73e46c37c971f 100644
--- a/tests/ui/check-cfg/target_feature.stderr
+++ b/tests/ui/check-cfg/target_feature.stderr
@@ -262,6 +262,8 @@ LL |     cfg!(target_feature = "_UNEXPECTED_VALUE");
 `ptx85`
 `ptx86`
 `ptx87`
+`ptx88`
+`ptx90`
 `quadword-atomics`
 `rand`
 `ras`
@@ -294,16 +296,29 @@ LL |     cfg!(target_feature = "_UNEXPECTED_VALUE");
 `sm4`
 `sm_100`
 `sm_100a`
+`sm_100f`
 `sm_101`
 `sm_101a`
+`sm_101f`
+`sm_103`
+`sm_103a`
+`sm_103f`
+`sm_110`
+`sm_110a`
+`sm_110f`
 `sm_120`
 `sm_120a`
+`sm_120f`
+`sm_121`
+`sm_121a`
+`sm_121f`
 `sm_70`
 `sm_72`
 `sm_75`
 `sm_80`
 `sm_86`
 `sm_87`
+`sm_88`
 `sm_89`
 `sm_90`
 `sm_90a`
diff --git a/tests/ui/target-feature/implied-features-nvptx.rs b/tests/ui/target-feature/implied-features-nvptx.rs
index a51c22afaf956..b4df58c8e05e8 100644
--- a/tests/ui/target-feature/implied-features-nvptx.rs
+++ b/tests/ui/target-feature/implied-features-nvptx.rs
@@ -1,28 +1,30 @@
-//@ assembly-output: emit-asm
-//@ compile-flags: --crate-type cdylib -C target-cpu=sm_80
-//@ only-nvptx64
-//@ build-pass
-#![no_std]
+//@ compile-flags: --target=nvptx64-nvidia-cuda --crate-type cdylib -C target-cpu=sm_90
+//@ needs-llvm-components: nvptx
+//@ check-pass
+//@ ignore-backends: gcc
+#![feature(no_core, rustc_attrs)]
+#![no_core]
 #![allow(dead_code)]
 
-#[panic_handler]
-pub fn panic(_info: &core::panic::PanicInfo) -> ! {
-    loop {}
+#[rustc_builtin_macro]
+#[macro_export]
+macro_rules! compile_error {
+    ($msg:expr $(,)?) => {{ /* compiler built-in */ }};
 }
 
-// -Ctarget-cpu=sm_80 directly enables sm_80 and ptx70
-#[cfg(not(all(target_feature = "sm_80", target_feature = "ptx70")))]
+// -Ctarget-cpu=sm_90 directly enables sm_90 and ptx78
+#[cfg(not(all(target_feature = "sm_90", target_feature = "ptx78")))]
 compile_error!("direct target features not enabled");
 
-// -Ctarget-cpu=sm_80 implies all earlier sm_* and ptx* features.
+// -Ctarget-cpu=sm_90 implies all earlier sm_* and ptx* features.
 #[cfg(not(all(
-    target_feature = "sm_60",
     target_feature = "sm_70",
-    target_feature = "ptx50",
-    target_feature = "ptx60",
+    target_feature = "sm_80",
+    target_feature = "ptx71",
+    target_feature = "ptx74",
 )))]
 compile_error!("implied target features not enabled");
 
-// -Ctarget-cpu=sm_80 implies all earlier sm_* and ptx* features.
-#[cfg(target_feature = "ptx71")]
-compile_error!("sm_80 requires only ptx70, but ptx71 enabled");
+// -Ctarget-cpu=sm_90 implies all earlier sm_* and ptx* features.
+#[cfg(target_feature = "ptx80")]
+compile_error!("sm_90 requires only ptx78, but ptx80 enabled");