diff --git a/.changeset/fancy-keys-hug.md b/.changeset/fancy-keys-hug.md
new file mode 100644
index 0000000000..59c216edc0
--- /dev/null
+++ b/.changeset/fancy-keys-hug.md
@@ -0,0 +1,5 @@
+---
+"@patternfly/pfe-tools": minor
+---
+
+Accept `tagPrefix` as an array of strings, supporting repos with multiple element prefixes
diff --git a/.pfe.config.json b/.pfe.config.json
index 02fa929c23..396a061159 100644
--- a/.pfe.config.json
+++ b/.pfe.config.json
@@ -1,4 +1,4 @@
 {
   "renderTitleInOverview": false,
-  "tagPrefix": "pf-v5"
+  "tagPrefix": ["pf-v5", "pf-v6"]
 }
diff --git a/tools/pfe-tools/11ty/DocsPage.ts b/tools/pfe-tools/11ty/DocsPage.ts
index 108687687b..db7b7264bc 100644
--- a/tools/pfe-tools/11ty/DocsPage.ts
+++ b/tools/pfe-tools/11ty/DocsPage.ts
@@ -26,7 +26,8 @@ export class DocsPage {
     this.docsTemplatePath = options?.docsTemplatePath;
     this.summary = this.manifest.getSummary(this.tagName);
     this.description = this.manifest.getDescription(this.tagName);
-    const prefix = `${config.tagPrefix.replace(/-$/, '')}-`;
+    const prefixes = [config.tagPrefix].flat().map(p => `${p.replace(/-$/, '')}-`);
+    const prefix = prefixes.find(p => this.tagName.startsWith(p)) ?? prefixes[0];
     const aliased = config.aliases[this.tagName] ?? this.tagName.replace(prefix, '');
     this.title = options?.title ?? Manifest.prettyTag(this.tagName, config.aliases, prefix);
     this.slug = slugify(aliased, { strict: true, lower: true });
diff --git a/tools/pfe-tools/11ty/plugins/types.ts b/tools/pfe-tools/11ty/plugins/types.ts
index f8ac6ef0f1..f1da145515 100644
--- a/tools/pfe-tools/11ty/plugins/types.ts
+++ b/tools/pfe-tools/11ty/plugins/types.ts
@@ -4,7 +4,7 @@ import type { Manifest } from '@patternfly/pfe-tools/custom-elements-manifest/li
 export interface DemoRecord {
   title: string;
   tagName: string;
-  tagPrefix: string;
+  tagPrefix: string | string[];
   primaryElementName: string;
   manifest: Manifest;
   slug: string;
diff --git a/tools/pfe-tools/config.ts b/tools/pfe-tools/config.ts
index 11921bfdff..895fde4de3 100644
--- a/tools/pfe-tools/config.ts
+++ b/tools/pfe-tools/config.ts
@@ -30,8 +30,8 @@ export interface PfeConfig {
   sourceControlURLPrefix?: string ;
   /** absolute URL prefix for demos, with trailing slash. Default 'https://patternflyelements.org/' */
   demoURLPrefix?: string ;
-  /** custom elements namespace. Default 'pf' */
-  tagPrefix?: string;
+  /** custom elements namespace. Default 'pf'. Accepts an array for repos with multiple prefixes. */
+  tagPrefix?: string | string[];
   /** Dev Server site options */
   site?: SiteOptions;
 }
@@ -102,6 +102,8 @@ export function deslugify(
   rootDir: string = process.cwd(),
 ): string {
   const { slugs, config } = getSlugsMap(rootDir);
-  const prefixedSlug = (slug.startsWith(`${config.tagPrefix}-`)) ? slug : `${config.tagPrefix}-${slug}`;
+  const prefixes = [config.tagPrefix].flat();
+  const hasPrefix = prefixes.some(p => slug.startsWith(`${p}-`));
+  const prefixedSlug = hasPrefix ? slug : `${prefixes[0]}-${slug}`;
   return slugs.get(slug) ?? prefixedSlug;
 }
diff --git a/tools/pfe-tools/custom-elements-manifest/lib/Manifest.ts b/tools/pfe-tools/custom-elements-manifest/lib/Manifest.ts
index 032e3ccfeb..b6f11967ab 100644
--- a/tools/pfe-tools/custom-elements-manifest/lib/Manifest.ts
+++ b/tools/pfe-tools/custom-elements-manifest/lib/Manifest.ts
@@ -324,7 +324,8 @@ export class Manifest {
       const [last = ''] = filePath.split(path.sep).reverse();
       const filename = last.replace('.html', '');
       const isMainElementDemo = filename === 'index';
-      const prefix = `${options.tagPrefix.replace(/-$/, '')}-`;
+      const prefixes = [options.tagPrefix].flat().map(p => `${p.replace(/-$/, '')}-`);
+      const prefix = prefixes.find(p => tagName.startsWith(p)) ?? prefixes[0];
       const title = isMainElementDemo ? prettyTag(tagName, options.aliases, prefix)
         : last
             .replace(/(?:^|[-/\s])\w/g, x => x.toUpperCase())
diff --git a/tools/pfe-tools/test/config.ts b/tools/pfe-tools/test/config.ts
index cfce355d59..60b7c897ba 100644
--- a/tools/pfe-tools/test/config.ts
+++ b/tools/pfe-tools/test/config.ts
@@ -50,7 +50,8 @@ const exists = async (path: string | URL) => {
 export function pfeTestRunnerConfig(opts: PfeTestRunnerConfigOptions): TestRunnerConfig {
   const { open, ...devServerConfig } = pfeDevServerConfig({ ...opts, loadDemo: false });
 
-  const { elementsDir, tagPrefix } = getPfeConfig();
+  const { elementsDir, tagPrefix: rawPrefix } = getPfeConfig();
+  const tagPrefixes = [rawPrefix].flat();
 
   const configuredReporter = opts.reporter ?? 'default';
 
@@ -121,7 +122,7 @@ export function pfeTestRunnerConfig(opts: PfeTestRunnerConfigOptions): TestRunne
        */
       async function(ctx, next) {
         if (ctx.path.endsWith('.js')
-            && ctx.path.startsWith(`/${elementsDir}/${tagPrefix}-`)
+            && tagPrefixes.some(p => ctx.path.startsWith(`/${elementsDir}/${p}-`))
             && await exists(`./${ctx.path}`.replace('.js', '.ts').replace('//', '/'))) {
           ctx.redirect(ctx.path.replace('.js', '.ts'));
         } else {