diff --git a/src/ontology/uberon-edit.obo b/src/ontology/uberon-edit.obo
index 38320a08d..8878e15fb 100644
--- a/src/ontology/uberon-edit.obo
+++ b/src/ontology/uberon-edit.obo
@@ -229,6 +229,17 @@ relationship: present_in_taxon NCBITaxon:33208 ! Metazoa
 relationship: present_in_taxon NCBITaxon:4751 ! Fungi
 property_value: seeAlso "https://github.com/OBOFoundry/COB/issues/51" xsd:anyURI
 
+[Term]
+id: UBERON:0000001 ! gross anatomical part
+name: gross anatomical part
+def: "Anatomical structure that is part of a multicellular organism and is at the gross anatomical level, e.g. above the level of a cell.  Included are portions of organism substances such as blood, multi-cell-part structures such as axon tracts, acellular anatomical structures such as hair, and organism subdivisions such as head. Excluded is the whole organism and more granular parts of the organism, such as atoms, molecules, macromolecular complexes and cells." [CARO:0001008]
+xref: CARO:0001008
+disjoint_from: GO:0005623 ! cell
+disjoint_from: GO:0110165 ! cellular anatomical entity
+disjoint_from: UBERON:0000468 ! multicellular organism
+is_a: UBERON:0000465 ! material anatomical entity
+relationship: present_in_taxon NCBITaxon:2759 ! Eukaryota
+
 [Term]
 id: UBERON:0000002
 name: uterine cervix
@@ -6811,7 +6822,7 @@ xref: TGMA:0001824
 xref: VHOG:0001726
 xref: XAO:0004001
 xref: ZFA:0001487
-is_a: UBERON:0000465 ! material anatomical entity
+is_a: UBERON:0000001 ! gross anatomical part
 relationship: has_quality PATO:0002198 ! quality of a substance
 relationship: part_of UBERON:0000468 {notes="this relationship may be too strong and may be weakened in future"} ! multicellular organism
 relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae
@@ -7225,7 +7236,7 @@ xref: TAO:0000382
 xref: TGMA:0001841
 xref: XAO:0003162
 xref: ZFA:0000382
-is_a: UBERON:0000061 ! anatomical structure
+is_a: UBERON:0000001 ! gross anatomical part
 disjoint_from: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure
 relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae
 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa
@@ -101334,7 +101345,7 @@ xref: CALOHA:TS-2122
 xref: EHDAA2:0003125
 xref: FMA:292313
 xref: MIAA:0000019
-is_a: UBERON:0000465 ! material anatomical entity
+is_a: UBERON:0000001 ! gross anatomical part
 relationship: capable_of GO:0032502 ! developmental process
 relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae
 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa
@@ -156284,7 +156295,6 @@ synonym: "midline birth canal" RELATED []
 intersection_of: UBERON:0000996 ! vagina
 intersection_of: connected_to UBERON:0013523 ! lateral vaginal canal
 intersection_of: intersects_midsagittal_plane_of UBERON:0003975 ! internal female genitalia
-relationship: channel_for UBERON:0000922 ! embryo
 relationship: in_taxon NCBITaxon:9263 {editor="cjm"} ! Metatheria
 
 [Term]
@@ -187555,7 +187565,7 @@ def: "Material anatomical entity that forms the outermost boundary of an anatomi
 subset: common_anatomy
 xref: AAO:0010270
 xref: ZFA:0005594
-is_a: UBERON:0000465 ! material anatomical entity
+is_a: UBERON:0000001 ! gross anatomical part
 relationship: bounding_layer_of UBERON:0000061 ! anatomical structure
 relationship: present_in_taxon NCBITaxon:33090 ! Viridiplantae
 relationship: present_in_taxon NCBITaxon:33208 ! Metazoa
@@ -220609,7 +220619,7 @@ relationship: in_taxon NCBITaxon:50557 ! Insecta
 id: UBERON:6040005
 name: insect synaptic neuropil
 def: "The part of the neuropil consisting largely of synapsing neuron projections." [FlyBase:FBrf0224194]
-is_a: UBERON:0000465 ! material anatomical entity
+is_a: UBERON:0000001 ! gross anatomical part
 relationship: in_taxon NCBITaxon:50557 ! Insecta
 relationship: part_of UBERON:0002606 ! neuropil