To help with approximate reconstruction of genotype likelihoods from binned DP (when downstream tools strictly require them to be present even in non-variant cells):
- during encoding, calculate regression coefficients for PL[1] and PL[2] on binned DP
- include them in the output file, perhaps in the header (but that'd require a second pass)
- optionally use them to fill out approximate PL vectors during decoding
To help with approximate reconstruction of genotype likelihoods from binned DP (when downstream tools strictly require them to be present even in non-variant cells):