diff --git a/pyproject.toml b/pyproject.toml
index 55562750..0113e035 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -60,6 +60,7 @@ build-backend = "flit_core.buildapi"
 
 [dependency-groups]
 docs = ["Sphinx", "sphinx-issues", "furo"]
+lint = ["pre-commit>=3.5,<5.0"]
 tests = [
   "pytest",
   "pytest-asyncio",
@@ -96,7 +97,12 @@ test-all-frameworks = [
   { include-group = "test-aiohttp" },
 ]
 
-dev = ["tox", "pre-commit>=3.5,<5.0", { include-group = "tests" }]
+dev = [
+  { include-group = "tests" },
+  { include-group = "lint" },
+  "tox",
+  "tox-uv",
+]
 
 [tool.uv]
 exclude-newer = "1 week"
diff --git a/tox.ini b/tox.ini
index 7f2ab09a..11be0891 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,4 +1,5 @@
 [tox]
+requires = tox-uv
 envlist=
     lint
     py{310,311,312,313,314}-marshmallow
@@ -7,22 +8,28 @@ envlist=
     docs
 
 [testenv]
+runner = uv-venv-lock-runner
 dependency_groups = test-all-frameworks
-deps =
-    marshmallow: marshmallow>=4.0.0,<5.0.0
-    marshmallowdev: https://github.com/marshmallow-code/marshmallow/archive/dev.tar.gz
-    lowest: flask==3.1.0
-    lowest: Django==5.2.0
-    lowest: bottle==0.13.0
-    lowest: tornado==6.5.0
-    lowest: pyramid==2.0.2
-    lowest: falcon==4.1.0
-    lowest: aiohttp==3.13.0
-    lowest: marshmallow==4.0.0
 commands = pytest {posargs}
 
+[testenv:py314-marshmallowdev]
+runner = uv-venv-runner
+deps = https://github.com/marshmallow-code/marshmallow/archive/dev.tar.gz
+
+[testenv:py310-lowest]
+runner = uv-venv-runner
+deps =
+    flask==3.1.0
+    Django==5.2.0
+    bottle==0.13.0
+    tornado==6.5.0
+    pyramid==2.0.2
+    falcon==4.1.0
+    aiohttp==3.13.0
+    marshmallow==4.0.0
+
 [testenv:lint]
-deps = pre-commit~=4.0
+dependency_groups = lint
 skip_install = true
 commands = pre-commit run --all-files
 
@@ -30,6 +37,7 @@ commands = pre-commit run --all-files
 # `webargs` and `marshmallow` both installed is a valuable safeguard against
 # issues in which `mypy` running on every file standalone won't catch things
 [testenv:mypy]
+runner = uv-venv-runner
 deps = mypy==1.11.0
 extras = frameworks
 commands = mypy src/ {posargs}
@@ -41,12 +49,13 @@ commands = sphinx-build docs/ {posargs:docs/_build}
 ; Below tasks are for development only (not run in CI)
 
 [testenv:docs-serve]
+runner = uv-venv-runner
 deps = sphinx-autobuild
 dependency_groups = docs
 commands = sphinx-autobuild --port=0 --open-browser --delay=2 docs/ docs/_build {posargs} --watch src --watch README.rst
 
 [testenv:readme-serve]
+runner = uv-venv-runner
 deps = restview
 skip_install = true
 commands = restview README.rst
-
diff --git a/uv.lock b/uv.lock
index 0d76b97f..8a9b8cf0 100644
--- a/uv.lock
+++ b/uv.lock
@@ -9,7 +9,7 @@ resolution-markers = [
 ]
 
 [options]
-exclude-newer = "0001-01-01T00:00:00Z" # This has no effect and is included for backwards compatibility when using relative exclude-newer values.
+exclude-newer = "2026-06-12T14:07:35.453016708Z"
 exclude-newer-span = "P1W"
 
 [[package]]
@@ -1780,6 +1780,32 @@ wheels = [
     { url = "https://files.pythonhosted.org/packages/bb/fd/394f00f3d3e23d87eb7b20276d88fe835e48780d3eb30e6f362428bb80c8/tox-4.55.1-py3-none-any.whl", hash = "sha256:e2084be6dfdef96ba1bed4948e6a1f73613d6952e1477be5dca45653d4c053c8", size = 215360, upload-time = "2026-06-03T20:01:01.967Z" },
 ]
 
+[[package]]
+name = "tox-uv"
+version = "1.35.2"
+source = { registry = "https://pypi.org/simple" }
+dependencies = [
+    { name = "tox-uv-bare" },
+    { name = "uv" },
+]
+wheels = [
+    { url = "https://files.pythonhosted.org/packages/ca/dc/6e9994c799bdbb309f829dd6b8d98764dd0757302f3433c380438a3a127b/tox_uv-1.35.2-py3-none-any.whl", hash = "sha256:2d99b0e3c782ba49e7cbe521c8d344758595961b17a3633738d67096641c1bde", size = 6565, upload-time = "2026-05-05T01:34:16.07Z" },
+]
+
+[[package]]
+name = "tox-uv-bare"
+version = "1.35.2"
+source = { registry = "https://pypi.org/simple" }
+dependencies = [
+    { name = "packaging" },
+    { name = "tomli", marker = "python_full_version < '3.11'" },
+    { name = "tox" },
+]
+sdist = { url = "https://files.pythonhosted.org/packages/0a/cb/168dc1ccf24e4065a9a0a33df55709ed2b5eb73bd2b13ddd53187e5dffb8/tox_uv_bare-1.35.2.tar.gz", hash = "sha256:49e28a804c97f23ea17e25859960c0fa78f35bccb7e14344cfd840e89a9aade9", size = 32333, upload-time = "2026-05-05T01:34:18.916Z" }
+wheels = [
+    { url = "https://files.pythonhosted.org/packages/5f/53/4a33dc81da39db7b31e5622333df361e8fe055b7ec636bd5fea762c9182d/tox_uv_bare-1.35.2-py3-none-any.whl", hash = "sha256:c0d590a41d1054a1ad0874e9e5943ff52402786e3d4599d8f8d37a65b566ef53", size = 22307, upload-time = "2026-05-05T01:34:17.681Z" },
+]
+
 [[package]]
 name = "translationstring"
 version = "1.4"
@@ -1816,6 +1842,32 @@ wheels = [
     { url = "https://files.pythonhosted.org/packages/7f/3e/5db95bcf282c52709639744ca2a8b149baccf648e39c8cc87553df9eae0c/urllib3-2.7.0-py3-none-any.whl", hash = "sha256:9fb4c81ebbb1ce9531cce37674bbc6f1360472bc18ca9a553ede278ef7276897", size = 131087, upload-time = "2026-05-07T16:13:17.151Z" },
 ]
 
+[[package]]
+name = "uv"
+version = "0.11.21"
+source = { registry = "https://pypi.org/simple" }
+sdist = { url = "https://files.pythonhosted.org/packages/f3/f9/f45bb1c251962ee614afd58ccd3dc06ada7869d04987efc2858a81cc4e0f/uv-0.11.21.tar.gz", hash = "sha256:083882c73373a16de4c136d54e3386a52388dead5048a07505e25578b157182f", size = 4259001, upload-time = "2026-06-11T18:18:26.468Z" }
+wheels = [
+    { url = "https://files.pythonhosted.org/packages/6f/a5/1c863b931f3aba6e07547929b8cb45875038de00678bfd2fbabcd76faeef/uv-0.11.21-py3-none-linux_armv6l.whl", hash = "sha256:48c36eb170a5e7a668c1d13d2c8edeb017a3e6484c224f1521b540a6bda9e50b", size = 23747368, upload-time = "2026-06-11T18:19:21.724Z" },
+    { url = "https://files.pythonhosted.org/packages/9b/8c/66d22f9152a014fbb17b1308394efe274e860b8beb4933f051396f96dd9f/uv-0.11.21-py3-none-macosx_10_12_x86_64.whl", hash = "sha256:88d8283f6ea9f0cdbb7717e6e08e916c32a8b8b7e11c72fcc6426a4c4eeb89e0", size = 22992460, upload-time = "2026-06-11T18:18:33.543Z" },
+    { url = "https://files.pythonhosted.org/packages/a5/f7/31d62c17837c9ae79cc6d5351fc5d54e8926e78b0315b4b6c187e0d1d50d/uv-0.11.21-py3-none-macosx_11_0_arm64.whl", hash = "sha256:9c11169a049ec8bf9ddc6a9f55fba9a240942ec8005faaaf4393f00ff7a4c16e", size = 21762931, upload-time = "2026-06-11T18:18:41.155Z" },
+    { url = "https://files.pythonhosted.org/packages/3c/04/c5503fc1015095db71c280526f45537f3bb06855ce281ff1761b85d149bf/uv-0.11.21-py3-none-manylinux_2_17_aarch64.manylinux2014_aarch64.musllinux_1_1_aarch64.whl", hash = "sha256:00193e4e077c27ee3d66da356744dbf0b3aa59356dfbd9a9efb1dc8469af8ad7", size = 23716032, upload-time = "2026-06-11T18:19:17.03Z" },
+    { url = "https://files.pythonhosted.org/packages/13/ac/46132335772fcdc38e5b5ec76701a8df8e3707605909b5fed46783689501/uv-0.11.21-py3-none-manylinux_2_17_armv7l.manylinux2014_armv7l.musllinux_1_1_armv7l.whl", hash = "sha256:870f48082df673016f465b068f40ad5aa7d2d3cfbcfb4e73724630684003a2ab", size = 23330010, upload-time = "2026-06-11T18:19:00.825Z" },
+    { url = "https://files.pythonhosted.org/packages/8c/d4/cfa1ea36706c32006dea9bf0a819b56c22af8270ea3a2b57562ce96c2d45/uv-0.11.21-py3-none-manylinux_2_17_armv7l.manylinux2014_armv7l.whl", hash = "sha256:af08e0d8f43da43bc68930aee56ca5f38ccfbc79d45b6e8a7d5051f1e975684f", size = 23339731, upload-time = "2026-06-11T18:18:52.395Z" },
+    { url = "https://files.pythonhosted.org/packages/96/c5/b34d3cdf05a069c583ef368e6db90242f842d7eb26b246981b3ca8799c27/uv-0.11.21-py3-none-manylinux_2_17_i686.manylinux2014_i686.whl", hash = "sha256:4530761c565f3a519a68f36628ee51f2b467b66573e2023e9073641219b60d23", size = 24657820, upload-time = "2026-06-11T18:19:25.62Z" },
+    { url = "https://files.pythonhosted.org/packages/be/b9/89b4e3909111c14311d4a1551afb37f0669587dc1f4ae7e26ec5baea6c09/uv-0.11.21-py3-none-manylinux_2_17_ppc64le.manylinux2014_ppc64le.whl", hash = "sha256:66906cfa7c29c2cf4ea5117cf5614b0b83078ff669e664e2187071fcb24c85c1", size = 25744586, upload-time = "2026-06-11T18:19:09.311Z" },
+    { url = "https://files.pythonhosted.org/packages/1c/7b/51d53d9fb1aaf38a613c2d20b40583ee2aa47fc000724a00aecbd5e61431/uv-0.11.21-py3-none-manylinux_2_17_s390x.manylinux2014_s390x.whl", hash = "sha256:525ef0eb56ff982357a321eca953307d824ab6f58473630c69521e8085f12b0a", size = 24990030, upload-time = "2026-06-11T18:18:29.618Z" },
+    { url = "https://files.pythonhosted.org/packages/de/70/3347f736911b73df1f31c0823d6502891f3c49fdeb157fe8060b18c08d1c/uv-0.11.21-py3-none-manylinux_2_17_x86_64.manylinux2014_x86_64.whl", hash = "sha256:b9ecdefa81db7e966d1655988cad6f840316228381dd69131ebc4ae9362bbccd", size = 25110133, upload-time = "2026-06-11T18:19:13.307Z" },
+    { url = "https://files.pythonhosted.org/packages/61/b5/b92538042d78550626ec7ac98b525bcb81ded8605c7ca9d6e35a1454ba71/uv-0.11.21-py3-none-manylinux_2_28_aarch64.whl", hash = "sha256:4ed98ff3165bf7b339692d0df918b87e6d36eb0bed5183466330d27d5730d57b", size = 23755172, upload-time = "2026-06-11T18:18:19.189Z" },
+    { url = "https://files.pythonhosted.org/packages/6a/1a/5c8993f95d4384baeaf00b96df0111af3c941a34e4466cde0d52b0b6ad99/uv-0.11.21-py3-none-manylinux_2_31_riscv64.musllinux_1_1_riscv64.whl", hash = "sha256:0e7916874f125a6f6af4cddd95f892ef19a4bb65c146afea7e544b0f98c63d02", size = 24468447, upload-time = "2026-06-11T18:19:04.572Z" },
+    { url = "https://files.pythonhosted.org/packages/66/2c/d4db24f9aeab8fce106633cd0388df4c0cf9f0991a2b5d9f58d061a031f7/uv-0.11.21-py3-none-manylinux_2_31_riscv64.whl", hash = "sha256:05e2f2e0fbf7c423f8287011ba0d2d69464f26a5f13b33df05cd491fbe5a910a", size = 24564716, upload-time = "2026-06-11T18:19:29.559Z" },
+    { url = "https://files.pythonhosted.org/packages/f6/53/c61711e81f9f8d34dd020340ace968499b2539d3bb4ac09d39339df54a9d/uv-0.11.21-py3-none-musllinux_1_1_i686.whl", hash = "sha256:b756dd2b368d7cc4aeb48249d06e1250bfcf81f0313ff7d7ec2ccafcd3ee4c93", size = 23917742, upload-time = "2026-06-11T18:18:57.187Z" },
+    { url = "https://files.pythonhosted.org/packages/84/21/210a5562a6a0eddfbe4890eb48e67f167be0307e75f029ca46b8f6386e5d/uv-0.11.21-py3-none-musllinux_1_1_x86_64.whl", hash = "sha256:88668a27959df9188ff72b0314f6b14f6acf6090964bb0748974239183ecb51c", size = 25330418, upload-time = "2026-06-11T18:18:37.383Z" },
+    { url = "https://files.pythonhosted.org/packages/f8/3c/81979463de0278facaa59ed3940b9c62f25a68d737d1a6f11cc3f922fba3/uv-0.11.21-py3-none-win32.whl", hash = "sha256:a00c78f3eea6db7967d98a505b01b7d80354517c7ff34f51701949f39c7b53e6", size = 22633520, upload-time = "2026-06-11T18:18:44.992Z" },
+    { url = "https://files.pythonhosted.org/packages/3d/51/e682e060813424467f14ae964dd7022f8fc537fea5803b5aab0ba1eca9cc/uv-0.11.21-py3-none-win_amd64.whl", hash = "sha256:d956ba9470d5267cc0ea3d7572cac3bf045bc78adad5b031b5558c6df13d2e19", size = 25291878, upload-time = "2026-06-11T18:18:23.832Z" },
+    { url = "https://files.pythonhosted.org/packages/5a/ef/8b1d92f9501963ef8694bb17ad80ba9926d049240d2da0a4f879aa37f3e2/uv-0.11.21-py3-none-win_arm64.whl", hash = "sha256:f64a851e429e6afb96f3a0b688995757ed3697bf1078509e2da8220ffc9805cd", size = 23715885, upload-time = "2026-06-11T18:18:48.596Z" },
+]
+
 [[package]]
 name = "venusian"
 version = "3.1.1"
@@ -1867,6 +1919,7 @@ dev = [
     { name = "pytest-aiohttp" },
     { name = "pytest-asyncio" },
     { name = "tox" },
+    { name = "tox-uv" },
     { name = "webtest" },
     { name = "webtest-aiohttp" },
 ]
@@ -1877,6 +1930,9 @@ docs = [
     { name = "sphinx", version = "9.1.0", source = { registry = "https://pypi.org/simple" }, marker = "python_full_version >= '3.12'" },
     { name = "sphinx-issues" },
 ]
+lint = [
+    { name = "pre-commit" },
+]
 test-aiohttp = [
     { name = "aiohttp" },
     { name = "packaging" },
@@ -1983,6 +2039,7 @@ dev = [
     { name = "pytest-aiohttp", specifier = ">=0.3.0" },
     { name = "pytest-asyncio" },
     { name = "tox" },
+    { name = "tox-uv" },
     { name = "webtest", specifier = "==3.0.7" },
     { name = "webtest-aiohttp", specifier = "==2.0.0" },
 ]
@@ -1991,6 +2048,7 @@ docs = [
     { name = "sphinx" },
     { name = "sphinx-issues" },
 ]
+lint = [{ name = "pre-commit", specifier = ">=3.5,<5.0" }]
 test-aiohttp = [
     { name = "aiohttp", specifier = ">=3.13.0" },
     { name = "packaging", specifier = ">=17.0" },