diff --git a/src/Illuminate/Routing/Middleware/ThrottleRequestsWithRedis.php b/src/Illuminate/Routing/Middleware/ThrottleRequestsWithRedis.php
index 6fbe19b37536..0538bdd764e0 100644
--- a/src/Illuminate/Routing/Middleware/ThrottleRequestsWithRedis.php
+++ b/src/Illuminate/Routing/Middleware/ThrottleRequestsWithRedis.php
@@ -30,6 +30,13 @@ class ThrottleRequestsWithRedis extends ThrottleRequests
      */
     public $remaining = [];
 
+    /**
+     * The key prefix for Redis throttle keys.
+     *
+     * @var string
+     */
+    protected $keyPrefix = '';
+
     /**
      * Create a new request throttler.
      *
@@ -93,7 +100,7 @@ protected function handleRequest($request, Closure $next, array $limits)
     protected function tooManyAttempts($key, $maxAttempts, $decaySeconds)
     {
         $limiter = new DurationLimiter(
-            $this->getRedisConnection(), $key, $maxAttempts, $decaySeconds
+            $this->getRedisConnection(), $this->getKeyPrefix().$key, $maxAttempts, $decaySeconds
         );
 
         return tap($limiter->tooManyAttempts(), function () use ($key, $limiter) {
@@ -114,7 +121,7 @@ protected function tooManyAttempts($key, $maxAttempts, $decaySeconds)
     protected function hit($key, $maxAttempts, $decaySeconds)
     {
         $limiter = new DurationLimiter(
-            $this->getRedisConnection(), $key, $maxAttempts, $decaySeconds
+            $this->getRedisConnection(), $this->getKeyPrefix().$key, $maxAttempts, $decaySeconds
         );
 
         $limiter->acquire();
@@ -148,6 +155,33 @@ protected function getTimeUntilNextRetry($key)
         return $this->decaysAt[$key] - $this->currentTime();
     }
 
+    /**
+     * Get the prefix for Redis throttle keys.
+     *
+     * Override this method to provide a stable namespace for Redis keys,
+     * which is required in Redis environments where ACLs restrict access
+     * by key pattern.
+     *
+     * @return string
+     */
+    protected function getKeyPrefix()
+    {
+        return $this->keyPrefix;
+    }
+
+    /**
+     * Set the prefix for Redis throttle keys.
+     *
+     * @param  string  $prefix
+     * @return $this
+     */
+    public function setKeyPrefix($prefix)
+    {
+        $this->keyPrefix = $prefix;
+
+        return $this;
+    }
+
     /**
      * Get the Redis connection that should be used for throttling.
      *
diff --git a/tests/Integration/Http/ThrottleRequestsWithRedisTest.php b/tests/Integration/Http/ThrottleRequestsWithRedisTest.php
index bf60a39f0739..98750f3416aa 100644
--- a/tests/Integration/Http/ThrottleRequestsWithRedisTest.php
+++ b/tests/Integration/Http/ThrottleRequestsWithRedisTest.php
@@ -92,4 +92,37 @@ public function testItReturnsConfiguredResponseWhenUsingAfterLimit(): void
             $this->get('/')->assertTooManyRequests()->assertContent('ah ah ah');
         });
     }
+
+    public function testKeyPrefixIsPrependedToRedisKeys()
+    {
+        $this->ifRedisAvailable(function () {
+            Route::get('/', function () {
+                return 'yes';
+            })->middleware(ThrottleRequestsWithRedis::class.':2,1');
+
+            // Set a key prefix on the middleware
+            $this->app->resolving(ThrottleRequestsWithRedis::class, function ($middleware) {
+                $middleware->setKeyPrefix('throttle:');
+            });
+
+            $response = $this->withoutExceptionHandling()->get('/');
+            $this->assertSame('yes', $response->getContent());
+
+            // Verify the middleware works correctly with the prefix
+            $response = $this->withoutExceptionHandling()->get('/');
+            $this->assertSame('yes', $response->getContent());
+            $this->assertEquals(0, $response->headers->get('X-RateLimit-Remaining'));
+        });
+    }
+
+    public function testSetKeyPrefixReturnsSelf()
+    {
+        $limiter = $this->app->make(\Illuminate\Cache\RateLimiter::class);
+        $redis = $this->app->make(\Illuminate\Contracts\Redis\Factory::class);
+        $middleware = new ThrottleRequestsWithRedis($limiter, $redis);
+
+        $result = $middleware->setKeyPrefix('throttle:');
+
+        $this->assertSame($middleware, $result);
+    }
 }