diff --git a/packages/openapi-ts-tests/main/test/3.1.x.test.ts b/packages/openapi-ts-tests/main/test/3.1.x.test.ts
index 2ee3cacfe5..fd5a4f3a16 100644
--- a/packages/openapi-ts-tests/main/test/3.1.x.test.ts
+++ b/packages/openapi-ts-tests/main/test/3.1.x.test.ts
@@ -199,6 +199,22 @@ describe(`OpenAPI ${version}`, () => {
       }),
       description: 'handles contentMediaType schema property for file uploads',
     },
+    {
+      config: createConfig({
+        input: 'content-binary.json',
+        output: 'content-binary-zod',
+        plugins: ['@hey-api/typescript', 'zod'],
+      }),
+      description: 'generates z.instanceof(Blob/File) for binary format with zod',
+    },
+    {
+      config: createConfig({
+        input: 'content-media-type.yaml',
+        output: 'content-media-type-zod',
+        plugins: ['@hey-api/typescript', 'zod'],
+      }),
+      description: 'generates z.instanceof(Blob/File) for contentMediaType with zod',
+    },
     {
       config: createConfig({
         input: 'content-types.yaml',
diff --git a/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-binary-zod/index.ts b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-binary-zod/index.ts
new file mode 100644
index 0000000000..79c8f10876
--- /dev/null
+++ b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-binary-zod/index.ts
@@ -0,0 +1,3 @@
+// This file is auto-generated by @hey-api/openapi-ts
+
+export type { ClientOptions, GetBarData, GetBarResponse, GetBarResponses, GetFooData, GetFooResponse, GetFooResponses } from './types.gen';
diff --git a/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-binary-zod/types.gen.ts b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-binary-zod/types.gen.ts
new file mode 100644
index 0000000000..97bd27233b
--- /dev/null
+++ b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-binary-zod/types.gen.ts
@@ -0,0 +1,31 @@
+// This file is auto-generated by @hey-api/openapi-ts
+
+export type ClientOptions = {
+    baseUrl: `${string}://${string}` | (string & {});
+};
+
+export type GetFooData = {
+    body?: never;
+    path?: never;
+    query?: never;
+    url: '/foo';
+};
+
+export type GetFooResponses = {
+    200: string;
+};
+
+export type GetFooResponse = GetFooResponses[keyof GetFooResponses];
+
+export type GetBarData = {
+    body?: never;
+    path?: never;
+    query?: never;
+    url: '/bar';
+};
+
+export type GetBarResponses = {
+    200: Blob | File;
+};
+
+export type GetBarResponse = GetBarResponses[keyof GetBarResponses];
diff --git a/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-binary-zod/zod.gen.ts b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-binary-zod/zod.gen.ts
new file mode 100644
index 0000000000..26ce70a46a
--- /dev/null
+++ b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-binary-zod/zod.gen.ts
@@ -0,0 +1,19 @@
+// This file is auto-generated by @hey-api/openapi-ts
+
+import * as z from 'zod';
+
+export const zGetFooData = z.object({
+    body: z.never().optional(),
+    path: z.never().optional(),
+    query: z.never().optional()
+});
+
+export const zGetFooResponse = z.string();
+
+export const zGetBarData = z.object({
+    body: z.never().optional(),
+    path: z.never().optional(),
+    query: z.never().optional()
+});
+
+export const zGetBarResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
diff --git a/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-media-type-zod/index.ts b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-media-type-zod/index.ts
new file mode 100644
index 0000000000..1bfff2876b
--- /dev/null
+++ b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-media-type-zod/index.ts
@@ -0,0 +1,3 @@
+// This file is auto-generated by @hey-api/openapi-ts
+
+export type { ClientOptions, FileUploadRequest, FileUploadRequestTyped, UploadFileData, UploadFileResponses, UploadFileTypedData, UploadFileTypedResponses } from './types.gen';
diff --git a/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-media-type-zod/types.gen.ts b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-media-type-zod/types.gen.ts
new file mode 100644
index 0000000000..c955f20ecf
--- /dev/null
+++ b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-media-type-zod/types.gen.ts
@@ -0,0 +1,47 @@
+// This file is auto-generated by @hey-api/openapi-ts
+
+export type ClientOptions = {
+    baseUrl: `${string}://${string}` | (string & {});
+};
+
+export type FileUploadRequest = {
+    /**
+     * Binary file content
+     */
+    file: Blob | File;
+};
+
+export type FileUploadRequestTyped = {
+    /**
+     * Binary file content with explicit string type
+     */
+    file: Blob | File;
+};
+
+export type UploadFileData = {
+    body?: FileUploadRequest;
+    path?: never;
+    query?: never;
+    url: '/upload';
+};
+
+export type UploadFileResponses = {
+    /**
+     * OK
+     */
+    200: unknown;
+};
+
+export type UploadFileTypedData = {
+    body?: FileUploadRequestTyped;
+    path?: never;
+    query?: never;
+    url: '/upload-typed';
+};
+
+export type UploadFileTypedResponses = {
+    /**
+     * OK
+     */
+    200: unknown;
+};
diff --git a/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-media-type-zod/zod.gen.ts b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-media-type-zod/zod.gen.ts
new file mode 100644
index 0000000000..984b27838b
--- /dev/null
+++ b/packages/openapi-ts-tests/main/test/__snapshots__/3.1.x/content-media-type-zod/zod.gen.ts
@@ -0,0 +1,23 @@
+// This file is auto-generated by @hey-api/openapi-ts
+
+import * as z from 'zod';
+
+export const zFileUploadRequest = z.object({
+    file: z.union([z.instanceof(Blob), z.instanceof(File)])
+});
+
+export const zFileUploadRequestTyped = z.object({
+    file: z.union([z.instanceof(Blob), z.instanceof(File)])
+});
+
+export const zUploadFileData = z.object({
+    body: zFileUploadRequest.optional(),
+    path: z.never().optional(),
+    query: z.never().optional()
+});
+
+export const zUploadFileTypedData = z.object({
+    body: zFileUploadRequestTyped.optional(),
+    path: z.never().optional(),
+    query: z.never().optional()
+});
diff --git a/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/mini/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/mini/default/zod.gen.ts
index c158420b6a..f349b51316 100644
--- a/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/mini/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/mini/default/zod.gen.ts
@@ -63,7 +63,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -272,7 +272,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.optional(z.array(zModelWithString)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
diff --git a/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/v3/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/v3/default/zod.gen.ts
index 085bf6077f..1edb369e1e 100644
--- a/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/v3/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/v3/default/zod.gen.ts
@@ -63,7 +63,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -272,7 +272,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
diff --git a/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/v4/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/v4/default/zod.gen.ts
index 3fc713430a..705abc14d2 100644
--- a/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/v4/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v3/__snapshots__/2.0.x/v4/default/zod.gen.ts
@@ -63,7 +63,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -272,7 +272,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
diff --git a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/mini/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/mini/default/zod.gen.ts
index 91f87b838a..348a42275e 100644
--- a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/mini/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/mini/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.optional(z.array(zModelWithString)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.optional(z.array(zModelWithReadOnlyAndWriteOnly)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -1011,7 +1011,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.optional(z.array(zModelWithReadOnlyAndWriteOnlyWritable)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -1472,7 +1472,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.nullable(z.string())
     }),
@@ -1493,7 +1493,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.optional(z.never()),
@@ -1525,7 +1525,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.optional(z.string()),
+    file: z.optional(z.union([z.instanceof(Blob), z.instanceof(File)])),
     metadata: z.optional(z.object({
         foo: z.optional(z.string()),
         bar: z.optional(z.string())
@@ -1534,7 +1534,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.optional(z.object({
-        content: z.optional(z.string()),
+        content: z.optional(z.union([z.instanceof(Blob), z.instanceof(File)])),
         data: z.nullish(zModelWithString)
     })),
     path: z.optional(z.never()),
diff --git a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/v3/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/v3/default/zod.gen.ts
index ae765fb53b..f833f2cff6 100644
--- a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/v3/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/v3/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnly).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1011,7 +1011,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnlyWritable).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1472,7 +1472,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.string().nullable()
     }),
@@ -1493,7 +1493,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.never().optional(),
@@ -1525,7 +1525,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.string().optional(),
+    file: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
     metadata: z.object({
         foo: z.string().optional(),
         bar: z.string().optional()
@@ -1534,7 +1534,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.object({
-        content: z.string().optional(),
+        content: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
         data: zModelWithString.nullish()
     }).optional(),
     path: z.never().optional(),
diff --git a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/v4/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/v4/default/zod.gen.ts
index 9d6fb8aa97..e37d71cec1 100644
--- a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/v4/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.0.x/v4/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnly).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1011,7 +1011,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnlyWritable).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1472,7 +1472,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.string().nullable()
     }),
@@ -1493,7 +1493,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.never().optional(),
@@ -1525,7 +1525,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.string().optional(),
+    file: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
     metadata: z.object({
         foo: z.string().optional(),
         bar: z.string().optional()
@@ -1534,7 +1534,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.object({
-        content: z.string().optional(),
+        content: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
         data: zModelWithString.nullish()
     }).optional(),
     path: z.never().optional(),
diff --git a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/mini/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/mini/default/zod.gen.ts
index 92fc8ee9f1..41bd2dada1 100644
--- a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/mini/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/mini/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.optional(z.array(zModelWithString)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.optional(z.array(zModelWithReadOnlyAndWriteOnly)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -1020,7 +1020,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.optional(z.array(zModelWithReadOnlyAndWriteOnlyWritable)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -1490,7 +1490,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.nullable(z.string())
     }),
@@ -1511,7 +1511,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.optional(z.never()),
@@ -1543,7 +1543,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.optional(z.string()),
+    file: z.optional(z.union([z.instanceof(Blob), z.instanceof(File)])),
     metadata: z.optional(z.object({
         foo: z.optional(z.string()),
         bar: z.optional(z.string())
@@ -1552,7 +1552,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.optional(z.object({
-        content: z.optional(z.string()),
+        content: z.optional(z.union([z.instanceof(Blob), z.instanceof(File)])),
         data: z.nullish(zModelWithString)
     })),
     path: z.optional(z.never()),
diff --git a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/v3/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/v3/default/zod.gen.ts
index 497cd4c1ba..06fbc37f45 100644
--- a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/v3/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/v3/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnly).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1020,7 +1020,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnlyWritable).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1490,7 +1490,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.string().nullable()
     }),
@@ -1511,7 +1511,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.never().optional(),
@@ -1543,7 +1543,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.string().optional(),
+    file: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
     metadata: z.object({
         foo: z.string().optional(),
         bar: z.string().optional()
@@ -1552,7 +1552,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.object({
-        content: z.string().optional(),
+        content: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
         data: zModelWithString.nullish()
     }).optional(),
     path: z.never().optional(),
diff --git a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/v4/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/v4/default/zod.gen.ts
index 1aec887d3a..fbbae01df8 100644
--- a/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/v4/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v3/__snapshots__/3.1.x/v4/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnly).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1020,7 +1020,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnlyWritable).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1490,7 +1490,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.string().nullable()
     }),
@@ -1511,7 +1511,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.never().optional(),
@@ -1543,7 +1543,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.string().optional(),
+    file: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
     metadata: z.object({
         foo: z.string().optional(),
         bar: z.string().optional()
@@ -1552,7 +1552,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.object({
-        content: z.string().optional(),
+        content: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
         data: zModelWithString.nullish()
     }).optional(),
     path: z.never().optional(),
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/mini/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/mini/default/zod.gen.ts
index 1c82095287..8e81c57f77 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/mini/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/mini/default/zod.gen.ts
@@ -63,7 +63,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -272,7 +272,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.optional(z.array(zModelWithString)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/v3/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/v3/default/zod.gen.ts
index 9a52d13e94..35e8c5e3ae 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/v3/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/v3/default/zod.gen.ts
@@ -63,7 +63,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -272,7 +272,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/v4/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/v4/default/zod.gen.ts
index c8b413ed94..86bc0b1c4e 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/v4/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/2.0.x/v4/default/zod.gen.ts
@@ -63,7 +63,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -272,7 +272,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/mini/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/mini/default/zod.gen.ts
index b035545f74..e8ca647661 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/mini/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/mini/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.optional(z.array(zModelWithString)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.optional(z.array(zModelWithReadOnlyAndWriteOnly)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -1011,7 +1011,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.optional(z.array(zModelWithReadOnlyAndWriteOnlyWritable)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -1472,7 +1472,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.nullable(z.string())
     }),
@@ -1493,7 +1493,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.optional(z.never()),
@@ -1525,7 +1525,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.optional(z.string()),
+    file: z.optional(z.union([z.instanceof(Blob), z.instanceof(File)])),
     metadata: z.optional(z.object({
         foo: z.optional(z.string()),
         bar: z.optional(z.string())
@@ -1534,7 +1534,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.optional(z.object({
-        content: z.optional(z.string()),
+        content: z.optional(z.union([z.instanceof(Blob), z.instanceof(File)])),
         data: z.nullish(zModelWithString)
     })),
     path: z.optional(z.never()),
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/v3/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/v3/default/zod.gen.ts
index d4b71b4c79..2bce7ae5cb 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/v3/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/v3/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnly).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1011,7 +1011,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnlyWritable).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1472,7 +1472,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.string().nullable()
     }),
@@ -1493,7 +1493,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.never().optional(),
@@ -1525,7 +1525,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.string().optional(),
+    file: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
     metadata: z.object({
         foo: z.string().optional(),
         bar: z.string().optional()
@@ -1534,7 +1534,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.object({
-        content: z.string().optional(),
+        content: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
         data: zModelWithString.nullish()
     }).optional(),
     path: z.never().optional(),
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/v4/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/v4/default/zod.gen.ts
index 969175d39b..6e9e04d447 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/v4/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.0.x/v4/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnly).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1011,7 +1011,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnlyWritable).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1472,7 +1472,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.string().nullable()
     }),
@@ -1493,7 +1493,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.never().optional(),
@@ -1525,7 +1525,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.string().optional(),
+    file: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
     metadata: z.object({
         foo: z.string().optional(),
         bar: z.string().optional()
@@ -1534,7 +1534,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.object({
-        content: z.string().optional(),
+        content: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
         data: zModelWithString.nullish()
     }).optional(),
     path: z.never().optional(),
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/mini/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/mini/default/zod.gen.ts
index 6343339340..5f28a7d31e 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/mini/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/mini/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.optional(z.array(zModelWithString)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.optional(z.array(zModelWithReadOnlyAndWriteOnly)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -1020,7 +1020,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.optional(z.array(zModelWithReadOnlyAndWriteOnlyWritable)),
-    propWithFile: z.optional(z.array(z.string())),
+    propWithFile: z.optional(z.array(z.union([z.instanceof(Blob), z.instanceof(File)]))),
     propWithNumber: z.optional(z.array(z.number()))
 });
 
@@ -1490,7 +1490,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.nullable(z.string())
     }),
@@ -1511,7 +1511,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.optional(z.never()),
@@ -1543,7 +1543,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.optional(z.string()),
+    file: z.optional(z.union([z.instanceof(Blob), z.instanceof(File)])),
     metadata: z.optional(z.object({
         foo: z.optional(z.string()),
         bar: z.optional(z.string())
@@ -1552,7 +1552,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.optional(z.object({
-        content: z.optional(z.string()),
+        content: z.optional(z.union([z.instanceof(Blob), z.instanceof(File)])),
         data: z.nullish(zModelWithString)
     })),
     path: z.optional(z.never()),
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/mini/string-with-format/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/mini/string-with-format/zod.gen.ts
index 86a96fb59c..fc615e7f05 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/mini/string-with-format/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/mini/string-with-format/zod.gen.ts
@@ -3,5 +3,5 @@
 import * as z from 'zod/mini';
 
 export const zFoo = z.object({
-    foo: z.optional(z.array(z.union([z.string(), z.string()])))
+    foo: z.optional(z.array(z.union([z.union([z.instanceof(Blob), z.instanceof(File)]), z.string()])))
 });
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v3/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v3/default/zod.gen.ts
index 374d4eedcc..658804e5b0 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v3/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v3/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnly).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1020,7 +1020,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnlyWritable).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1490,7 +1490,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.string().nullable()
     }),
@@ -1511,7 +1511,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.never().optional(),
@@ -1543,7 +1543,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.string().optional(),
+    file: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
     metadata: z.object({
         foo: z.string().optional(),
         bar: z.string().optional()
@@ -1552,7 +1552,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.object({
-        content: z.string().optional(),
+        content: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
         data: zModelWithString.nullish()
     }).optional(),
     path: z.never().optional(),
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v3/string-with-format/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v3/string-with-format/zod.gen.ts
index 812ba4f250..e834e6fec1 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v3/string-with-format/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v3/string-with-format/zod.gen.ts
@@ -3,5 +3,5 @@
 import { z } from 'zod/v3';
 
 export const zFoo = z.object({
-    foo: z.array(z.union([z.string(), z.string()])).optional()
+    foo: z.array(z.union([z.union([z.instanceof(Blob), z.instanceof(File)]), z.string()])).optional()
 });
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v4/default/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v4/default/zod.gen.ts
index 217db289ab..f63a9847ed 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v4/default/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v4/default/zod.gen.ts
@@ -76,7 +76,7 @@ export const zNonAsciiStringæøåÆøÅöôêÊ字符串 = z.string();
 /**
  * This is a simple file
  */
-export const zSimpleFile = z.string();
+export const zSimpleFile = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 /**
  * This is a simple string
@@ -352,7 +352,7 @@ export const zModelWithNestedEnums = z.object({
  */
 export const zModelWithArray = z.object({
     prop: z.array(zModelWithString).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -775,7 +775,7 @@ export const zModelWithReadOnlyAndWriteOnly = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnly = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnly).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1020,7 +1020,7 @@ export const zModelWithReadOnlyAndWriteOnlyWritable = z.object({
  */
 export const zModelWithArrayReadOnlyAndWriteOnlyWritable = z.object({
     prop: z.array(zModelWithReadOnlyAndWriteOnlyWritable).optional(),
-    propWithFile: z.array(z.string()).optional(),
+    propWithFile: z.array(z.union([z.instanceof(Blob), z.instanceof(File)])).optional(),
     propWithNumber: z.array(z.number()).optional()
 });
 
@@ -1490,7 +1490,7 @@ export const zTypesResponse = z.union([
 ]);
 
 export const zUploadFileData = z.object({
-    body: z.string(),
+    body: z.union([z.instanceof(Blob), z.instanceof(File)]),
     path: z.object({
         'api-version': z.string().nullable()
     }),
@@ -1511,7 +1511,7 @@ export const zFileResponseData = z.object({
 /**
  * Success
  */
-export const zFileResponseResponse = z.string();
+export const zFileResponseResponse = z.union([z.instanceof(Blob), z.instanceof(File)]);
 
 export const zComplexTypesData = z.object({
     body: z.never().optional(),
@@ -1543,7 +1543,7 @@ export const zMultipartResponseData = z.object({
  * OK
  */
 export const zMultipartResponseResponse = z.object({
-    file: z.string().optional(),
+    file: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
     metadata: z.object({
         foo: z.string().optional(),
         bar: z.string().optional()
@@ -1552,7 +1552,7 @@ export const zMultipartResponseResponse = z.object({
 
 export const zMultipartRequestData = z.object({
     body: z.object({
-        content: z.string().optional(),
+        content: z.union([z.instanceof(Blob), z.instanceof(File)]).optional(),
         data: zModelWithString.nullish()
     }).optional(),
     path: z.never().optional(),
diff --git a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v4/string-with-format/zod.gen.ts b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v4/string-with-format/zod.gen.ts
index e19b0d8561..d16f7fabc8 100644
--- a/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v4/string-with-format/zod.gen.ts
+++ b/packages/openapi-ts-tests/zod/v4/__snapshots__/3.1.x/v4/string-with-format/zod.gen.ts
@@ -3,5 +3,5 @@
 import * as z from 'zod';
 
 export const zFoo = z.object({
-    foo: z.array(z.union([z.string(), z.string()])).optional()
+    foo: z.array(z.union([z.union([z.instanceof(Blob), z.instanceof(File)]), z.string()])).optional()
 });
diff --git a/packages/openapi-ts/src/plugins/zod/constants.ts b/packages/openapi-ts/src/plugins/zod/constants.ts
index 940c58f2c7..75e80495fb 100644
--- a/packages/openapi-ts/src/plugins/zod/constants.ts
+++ b/packages/openapi-ts/src/plugins/zod/constants.ts
@@ -22,6 +22,7 @@ export const identifiers = {
   gte: 'gte',
   guid: 'guid',
   infer: 'infer',
+  instanceof: 'instanceof',
   int: 'int',
   intersection: 'intersection',
   ip: 'ip',
diff --git a/packages/openapi-ts/src/plugins/zod/mini/toAst/string.ts b/packages/openapi-ts/src/plugins/zod/mini/toAst/string.ts
index be1dda9cc3..2b64ed17f1 100644
--- a/packages/openapi-ts/src/plugins/zod/mini/toAst/string.ts
+++ b/packages/openapi-ts/src/plugins/zod/mini/toAst/string.ts
@@ -23,6 +23,15 @@ function formatNode(ctx: StringResolverContext): ChainResult {
   const { z } = symbols;
 
   switch (schema.format) {
+    case 'binary':
+      return $(z)
+        .attr(identifiers.union)
+        .call(
+          $.array(
+            $(z).attr(identifiers.instanceof).call($.id('Blob')),
+            $(z).attr(identifiers.instanceof).call($.id('File')),
+          ),
+        );
     case 'date':
       return $(z).attr(identifiers.iso).attr(identifiers.date).call();
     case 'date-time': {
diff --git a/packages/openapi-ts/src/plugins/zod/v3/toAst/string.ts b/packages/openapi-ts/src/plugins/zod/v3/toAst/string.ts
index 45bb2b3c31..8590de0d3b 100644
--- a/packages/openapi-ts/src/plugins/zod/v3/toAst/string.ts
+++ b/packages/openapi-ts/src/plugins/zod/v3/toAst/string.ts
@@ -19,9 +19,19 @@ function constNode(ctx: StringResolverContext): ChainResult {
 }
 
 function formatNode(ctx: StringResolverContext): ChainResult {
-  const { chain, plugin, schema } = ctx;
+  const { chain, plugin, schema, symbols } = ctx;
+  const { z } = symbols;
 
   switch (schema.format) {
+    case 'binary':
+      return $(z)
+        .attr(identifiers.union)
+        .call(
+          $.array(
+            $(z).attr(identifiers.instanceof).call($.id('Blob')),
+            $(z).attr(identifiers.instanceof).call($.id('File')),
+          ),
+        );
     case 'date':
       return chain.current.attr(identifiers.date).call();
     case 'date-time': {
diff --git a/packages/openapi-ts/src/plugins/zod/v4/toAst/string.ts b/packages/openapi-ts/src/plugins/zod/v4/toAst/string.ts
index 5606660549..bcdf720556 100644
--- a/packages/openapi-ts/src/plugins/zod/v4/toAst/string.ts
+++ b/packages/openapi-ts/src/plugins/zod/v4/toAst/string.ts
@@ -23,6 +23,15 @@ function formatNode(ctx: StringResolverContext): ChainResult {
   const { z } = symbols;
 
   switch (schema.format) {
+    case 'binary':
+      return $(z)
+        .attr(identifiers.union)
+        .call(
+          $.array(
+            $(z).attr(identifiers.instanceof).call($.id('Blob')),
+            $(z).attr(identifiers.instanceof).call($.id('File')),
+          ),
+        );
     case 'date':
       return $(z).attr(identifiers.iso).attr(identifiers.date).call();
     case 'date-time': {