In https://github.com/dseguy/clearPHP/blob/master/rules/use-smart-autoload.md example:
function my_autoloader($class) {
include 'classes/' . $class . '.class.php';
}
For every include that fail, will generate a warning and increase your log. If you have 4 functions (methods,..) registered using include directly, will create 4 warnings for every request.
It is worse with require, that create a fatal error and stop the execution.
It 's a shame than spl_autoload_register don't work like include_path, that try every path and show the error if all fail.