Hi there,
I found that none of my shortcuts works yesterday, then when I tried to check the configs of shortkeys by clicking the extension icon on top bar, it seems blocked and the icon only show the click down intermediate highlighted state and nothing poped up, so I've tried to restart my Chrome several times then repeat the previmg-, after that, a brand new UI poped up and I realized that the extension updated with a major version, but none of my shortkeys configs show in the new UI config page.
I have to manully re-config all my shortkeys and it works now. Not sure if any of my extensions conflicted with shortkeys since I have lots of them.
Here is my chrome info.

Hi there,
I found that none of my shortcuts works yesterday, then when I tried to check the configs of shortkeys by clicking the extension icon on top bar, it seems blocked and the icon only show the click down intermediate highlighted state and nothing poped up, so I've tried to restart my Chrome several times then repeat the previmg-, after that, a brand new UI poped up and I realized that the extension updated with a major version, but none of my shortkeys configs show in the new UI config page.
I have to manully re-config all my shortkeys and it works now. Not sure if any of my extensions conflicted with shortkeys since I have lots of them.
Here is my chrome info.