Hi there, I am running ImpulseDE2 under a case-only design, identify DEGs over a continuous variable time, but the problem is that I have too many time points, even if I use the p-adj DEGs to draw a clustered heatmap (package pheatmap), it is not easy to tell whether a gene cluster is increasing or decreasing over so many timepoints.
So I just wonder if there is a way in ImpulseDE2 to help me classify the gene expression pattern into Up or Down, or do I need to refer to super-parameters in ImpulseDE2 model: to manually compare the initial amplitude h0 with the stable amplitude h2 for each gene?
Many thanks!