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# De novo Design of Biomolecular Interactions with RFdiffusion3
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RFdiffusion3 (RFD3) is a diffusion method that can design protein structures
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RFdiffusion3 (RFD3) is a diffusion method that can design biopolymer structures
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under complex constraints.
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This repository contains both the training and inference code, and
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For full details on how to specify inputs, see the [input specification documentation](./docs/input.md). You can also see `foundry/models/rfd3/configs/inference_engine/rfdiffusion3.yaml` for even more options.
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Nucleic acid design, along with proteins, is also possible using RFD3 using the atom23 checkpoints. For full details see the [atom23 design documentation](./docs/examples/atom23_design.md)
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## Further example JSONs for different applications
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Additional examples are broken up by use case. If you have cloned the
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repository, matching `.json` files are in `foundry/models/rfd3/docs/examples`
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