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# Allele-specific and genetically-regulated gene expression prediction
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We simulated log2 effect sizes for each eQTL from standard Normal distribution. Expected gene expression is estimated as the sum of the two haplotypic counts using a simulated e0, and the simulated sequencing read count for each gene is generated using a Poisson distribution. To generate simulated ASE data, we calculated the expected reference expression ratio for each individual, and simulated discrete read counts for each haplotype using Binomial distribution.
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We simulated log2 effect sizes for each eQTL from standard Normal distribution. Expected gene expression is estimated as the sum of the two haplotypic counts using a simulated e0 (expression for haplotype carrying reference allele), and the simulated sequencing read count for each gene is generated using a Poisson distribution. To generate simulated ASE data, we calculated the expected reference expression ratio for each individual, and simulated discrete read counts for each haplotype using Binomial distribution.
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## Inputs
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