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source/walkthroughs/Protein_protein_binder_design_with_RFdiffusion.ipynb

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"- `openprotein_python>=0.10`\n",
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"- `molviewspec` (for structure visualization)\n",
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"\n",
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"See the Python client [installation instructions](https://docs.openprotein.ai/python-api/installation.html) for more info.\n",
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"See the Python client [installation instructions](../python-api/installation.html) for more info.\n",
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"\n",
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"Additionally, you should have your [credentials set up](https:/docs.openprotein.ai/python-api/quickstart.html) in `~/.openprotein/config.toml` to authenticate with the OpenProtein.AI\n",
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"Additionally, you should have your [credentials set up](../python-api/quickstart.html) in `~/.openprotein/config.toml` to authenticate with the OpenProtein.AI\n",
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"API."
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]
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},
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"1. Expressed and purified for experimental validation\n",
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"2. Tested for binding affinity\n",
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"3. Further optimized through additional rounds of design, for example, with\n",
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" [OpenProtein.AI's property regression models](https://docs.openprotein.ai/python-api/property-regression-models/index.html).\n",
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" [OpenProtein.AI's property regression models](../python-api/property-regression-models/index.html).\n",
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"\n",
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"### Other resources\n",
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"\n",
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"Read more about our binder design workflows and other de novo design tools here:\n",
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"- [Designing de novo nanobody binders with BoltzGen and ProteinMPNN](https://docs.openprotein.ai/walkthroughs/Nanobody_binder_design_with_BoltzGen.html)\n",
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"- [Inverse folding for protein redesign](https://docs.openprotein.ai/walkthroughs/PoET-2_inverse_folding.html)\n",
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"- [Designing de novo nanobody binders with BoltzGen and ProteinMPNN](./Nanobody_binder_design_with_BoltzGen.ipynb)\n",
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"- [Inverse folding for protein redesign](./PoET-2_inverse_folding.ipynb)\n",
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"\n",
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"or see the detailed API references\n",
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"- [RFdiffusion](https://docs.openprotein.ai/python-api/api-reference/models.html#rfdiffusion)\n",
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"- [ProteinMPNN](https://docs.openprotein.ai/python-api/api-reference/models.html#proteinmpnn)\n",
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"- [Boltz-2](https://docs.openprotein.ai/python-api/api-reference/fold.html#openprotein.fold.Boltz2Model)"
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"- [RFdiffusion](../python-api/api-reference/models.html#rfdiffusion)\n",
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"- [ProteinMPNN](../python-api/api-reference/models.html#proteinmpnn)\n",
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"- [Boltz-2](../python-api/api-reference/fold.html#openprotein.fold.Boltz2Model)"
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]
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}
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],

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