As long as there is 1ml of the fuel stored in an HP tank, the engine can take the rest of the fuel from non-HP tanks.  (image from https://discord.com/channels/319857228905447436/684077440401932290/1348528701255581768) Relevant conversations: https://discord.com/channels/319857228905447436/1115321536807718992/1311245293043585044 https://discord.com/channels/319857228905447436/684077440401932290/1364246587408388216 Relevant code according to njits23: https://github.com/KSP-RO/RealFuels/blob/master/Source/Ullage/UllageSet.cs