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Why the cell numbers in ArchR project differed from the results from cellranger-atac #2318

@CampingOnSeabed

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@CampingOnSeabed

Hello,
I am using ArchR to analyse my single cell ATAC-seq data, but I noticed a difference in the cell numbers in the result of cellranger-atac between ArchR project. In my ArchR project, I got 20693 cells, while in the results of cellranger, it is 19256 cells.

I am unsure why this difference exists and would greatly appreciate your insights on:
Potential reasons for the cell count mismatch between ArchR and cellranger-atac
Recommended steps to validate and reconcile these cell numbers (e.g., filtering criteria, data processing steps)

Thank you very much for your time and assistance.

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