diff --git a/.gitignore b/.gitignore
index 66046e11..9befdf41 100644
--- a/.gitignore
+++ b/.gitignore
@@ -2,4 +2,5 @@
 **/*.rs.bk
 Cargo.lock
 /.idea
-.vscode
\ No newline at end of file
+.vscode
+.DS_Store
diff --git a/rocket-okapi-codegen/src/openapi_attr/doc_attr.rs b/rocket-okapi-codegen/src/doc_attr.rs
similarity index 96%
rename from rocket-okapi-codegen/src/openapi_attr/doc_attr.rs
rename to rocket-okapi-codegen/src/doc_attr.rs
index bfd6f202..676c390c 100644
--- a/rocket-okapi-codegen/src/openapi_attr/doc_attr.rs
+++ b/rocket-okapi-codegen/src/doc_attr.rs
@@ -31,7 +31,7 @@ fn merge_description_lines(doc: &str) -> Option<String> {
     none_if_empty(desc)
 }
 
-fn get_doc(attrs: &[Attribute]) -> Option<String> {
+pub fn get_doc(attrs: &[Attribute]) -> Option<String> {
     let doc = attrs
         .iter()
         .filter_map(|attr| {
diff --git a/rocket-okapi-codegen/src/lib.rs b/rocket-okapi-codegen/src/lib.rs
index 31a3b7e9..cc49523c 100644
--- a/rocket-okapi-codegen/src/lib.rs
+++ b/rocket-okapi-codegen/src/lib.rs
@@ -9,9 +9,11 @@
 //! - `#[derive(OpenApiFromRequest)]`: Implement `OpenApiFromRequest` trait for a given struct.
 //!
 
+mod doc_attr;
 mod openapi_attr;
 mod openapi_spec;
 mod parse_routes;
+mod responder_derive;
 
 use proc_macro::TokenStream;
 use quote::quote;
@@ -85,7 +87,7 @@ pub fn openapi_spec(input: TokenStream) -> TokenStream {
     .into()
 }
 
-/// Derive marco for the `OpenApiFromRequest` trait.
+/// Derive macro for the `OpenApiFromRequest` trait.
 ///
 /// This derive trait is a very simple implementation for anything that does not
 /// require any other special headers or parameters to be validated.
@@ -136,6 +138,21 @@ pub fn open_api_from_request_derive(input: TokenStream) -> TokenStream {
     gen.into()
 }
 
+/// Derive for the [`OpenApiResponderInner`](rocket_okapi::response::OpenApiResponderInner) trait.
+///
+/// Derive is fully compatible with the syntax of the
+/// [`#[response]`](https://api.rocket.rs/v0.5/rocket/derive.Responder#field-attribute) attribute
+/// from Rocket and does not require any code changes.
+#[proc_macro_derive(OpenApiResponder, attributes(responder))]
+pub fn open_api_responder_derive(input: TokenStream) -> TokenStream {
+    let ast: syn::DeriveInput = syn::parse(input).unwrap();
+
+    match responder_derive::derive(ast) {
+        Ok(v) => v.into(),
+        Err(err) => err.write_errors().into(),
+    }
+}
+
 fn get_add_operation_fn_name(route_fn_name: &Ident) -> Ident {
     Ident::new(
         &format!("okapi_add_operation_for_{}_", route_fn_name),
diff --git a/rocket-okapi-codegen/src/openapi_attr/mod.rs b/rocket-okapi-codegen/src/openapi_attr/mod.rs
index 67d88fe0..8a4e4685 100644
--- a/rocket-okapi-codegen/src/openapi_attr/mod.rs
+++ b/rocket-okapi-codegen/src/openapi_attr/mod.rs
@@ -1,7 +1,6 @@
-mod doc_attr;
 mod route_attr;
 
-use crate::get_add_operation_fn_name;
+use crate::{doc_attr::get_title_and_desc_from_doc, get_add_operation_fn_name};
 use darling::FromMeta;
 use proc_macro::TokenStream;
 use proc_macro2::Span;
@@ -295,7 +294,7 @@ fn create_route_operation_fn(
         .replace("..>", "}")
         .replace('>', "}");
     let method = Ident::new(&to_pascal_case_string(route.method), Span::call_site());
-    let (title, desc) = doc_attr::get_title_and_desc_from_doc(&route_fn.attrs);
+    let (title, desc) = get_title_and_desc_from_doc(&route_fn.attrs);
     let title = match title {
         Some(x) => quote!(Some(#x.to_owned())),
         None => quote!(None),
diff --git a/rocket-okapi-codegen/src/responder_derive/mod.rs b/rocket-okapi-codegen/src/responder_derive/mod.rs
new file mode 100644
index 00000000..961f2ad0
--- /dev/null
+++ b/rocket-okapi-codegen/src/responder_derive/mod.rs
@@ -0,0 +1,113 @@
+mod response_attr;
+
+use crate::doc_attr::get_doc;
+use darling::{FromMeta, Result};
+use proc_macro2::TokenStream;
+use quote::quote;
+use response_attr::ResponseAttribute;
+use syn::{parse_quote, Attribute, DeriveInput, Fields, GenericParam, Generics};
+
+pub fn derive(input: DeriveInput) -> Result<TokenStream> {
+    let responses_variants: Vec<(Vec<Attribute>, Fields)> = match input.data {
+        syn::Data::Struct(syn::DataStruct { fields, .. }) => {
+            [(input.attrs.clone(), fields)].to_vec()
+        }
+        syn::Data::Enum(syn::DataEnum { variants, .. }) => {
+            variants.into_iter().map(|v| (v.attrs, v.fields)).collect()
+        }
+        syn::Data::Union(_) => {
+            return Err(darling::Error::custom("unions are not supported").with_span(&input));
+        }
+    };
+
+    let name = input.ident;
+
+    let generics = add_trait_bound(input.generics);
+    let (impl_generics, ty_generics, where_clause) = generics.split_for_impl();
+
+    let responses = responses_variants
+        .into_iter()
+        .filter_map(|(variant_attrs, variant_fields)| {
+            variant_to_responses(&input.attrs, variant_attrs, variant_fields).transpose()
+        })
+        .collect::<Result<Vec<_>>>()?;
+
+    Ok(quote! {
+        impl #impl_generics ::rocket_okapi::response::OpenApiResponderInner for #name #ty_generics #where_clause {
+            fn responses(
+                gen: &mut ::rocket_okapi::gen::OpenApiGenerator,
+            ) -> ::rocket_okapi::Result<::rocket_okapi::okapi::openapi3::Responses> {
+                let mut responses = ::rocket_okapi::okapi::openapi3::Responses::default();
+                #(
+                    responses.responses.extend({ #responses }.responses);
+                )*
+                Ok(responses)
+            }
+        }
+    })
+}
+
+fn add_trait_bound(mut generics: Generics) -> Generics {
+    for param in generics.params.iter_mut() {
+        if let GenericParam::Type(param) = param {
+            param.bounds.push(parse_quote!(
+                ::rocket_okapi::response::OpenApiResponderInner
+            ));
+        }
+    }
+    generics
+}
+
+fn variant_to_responses(
+    entity_attrs: &[Attribute],
+    attrs: Vec<Attribute>,
+    fields: Fields,
+) -> Result<Option<TokenStream>> {
+    let response_attribute = get_response_attr_or_default(&attrs)?;
+
+    let field = fields
+        .into_iter()
+        .next()
+        .ok_or(darling::Error::custom("need at least one field"))?;
+    let response_type = &field.ty;
+
+    let status = response_attribute.status;
+    let set_status =
+        status.map(|status| quote! { ::rocket_okapi::util::set_status_code(&mut r, #status)?; });
+
+    let content_type = response_attribute.content_type;
+    let set_content_type =
+        content_type.map(|ct| quote! { ::rocket_okapi::util::set_content_type(&mut r, #ct)?; });
+
+    let description = get_doc(&field.attrs)
+        .or_else(|| get_doc(&attrs))
+        .or_else(|| get_doc(entity_attrs));
+    let set_description =
+        description.map(|doc| quote! { ::rocket_okapi::util::set_description(&mut r, #doc)?; });
+
+    Ok(Some(quote! {
+        let mut r = <#response_type as ::rocket_okapi::response::OpenApiResponderInner>::responses(gen)?;
+        #set_status
+        #set_content_type
+        #set_description
+        r
+    }))
+}
+
+fn get_response_attr_or_default(attrs: &[Attribute]) -> Result<ResponseAttribute> {
+    let mut attrs = attrs.iter().filter(|a| a.path.is_ident("response"));
+
+    let Some(attr) = attrs.next() else {
+        return Ok(ResponseAttribute::default());
+    };
+
+    if let Some(second_attr) = attrs.next() {
+        return Err(
+            darling::Error::custom("`response` attribute may be specified only once")
+                .with_span(second_attr),
+        );
+    }
+
+    let meta = attr.parse_meta()?;
+    ResponseAttribute::from_meta(&meta)
+}
diff --git a/rocket-okapi-codegen/src/responder_derive/response_attr.rs b/rocket-okapi-codegen/src/responder_derive/response_attr.rs
new file mode 100644
index 00000000..0174b98d
--- /dev/null
+++ b/rocket-okapi-codegen/src/responder_derive/response_attr.rs
@@ -0,0 +1,63 @@
+use darling::FromMeta;
+use quote::ToTokens;
+
+/// This structure documents all the properties that can be used in
+/// the `#[response]` attribute. For example: `#[response(status = 404)]`
+#[derive(Default, FromMeta)]
+#[darling(default)]
+pub struct ResponseAttribute {
+    /// Status code of the response. By default, depends on the field type
+    pub status: Option<Status>,
+
+    /// Content type of the response. By default, depends on the field type
+    pub content_type: Option<ContentType>,
+}
+
+/// Derive macro wrapper for the Rocket's Status type.
+/// Implements [`darling::FromMeta`] and [`quote::ToTokens`].
+pub struct Status(pub rocket_http::Status);
+
+impl Default for Status {
+    fn default() -> Self {
+        Self(rocket_http::Status::Ok)
+    }
+}
+
+impl FromMeta for Status {
+    fn from_value(value: &syn::Lit) -> darling::Result<Self> {
+        let syn::Lit::Int(int) = value else {
+            return Err(darling::Error::unexpected_lit_type(value));
+        };
+
+        let code = int.base10_parse::<u16>()?;
+        if code < 100 || code >= 600 {
+            return Err(darling::Error::custom("status must be in range [100, 599]").with_span(int));
+        }
+
+        Ok(Self(rocket_http::Status::new(code)))
+    }
+}
+
+impl ToTokens for Status {
+    fn to_tokens(&self, tokens: &mut proc_macro2::TokenStream) {
+        self.0.code.to_tokens(tokens);
+    }
+}
+
+/// Derive macro wrapper for the Rocket's ContentType type.
+/// Implements [`darling::FromMeta`] and [`quote::ToTokens`].
+pub struct ContentType(pub rocket_http::ContentType);
+
+impl FromMeta for ContentType {
+    fn from_string(value: &str) -> darling::Result<Self> {
+        rocket_http::ContentType::parse_flexible(value)
+            .map(Self)
+            .ok_or_else(|| darling::Error::unsupported_format(value))
+    }
+}
+
+impl ToTokens for ContentType {
+    fn to_tokens(&self, tokens: &mut proc_macro2::TokenStream) {
+        self.0.to_string().to_tokens(tokens);
+    }
+}
diff --git a/rocket-okapi/src/util.rs b/rocket-okapi/src/util.rs
index b19a8c9b..e6e3396f 100644
--- a/rocket-okapi/src/util.rs
+++ b/rocket-okapi/src/util.rs
@@ -123,6 +123,15 @@ pub fn set_content_type(responses: &mut Responses, content_type: impl ToString)
     Ok(())
 }
 
+/// Replaces the description for all responses.
+pub fn set_description(responses: &mut Responses, description: impl ToString) -> Result<()> {
+    for ref mut resp_refor in responses.responses.values_mut() {
+        let response = ensure_not_ref(resp_refor)?;
+        response.description = description.to_string();
+    }
+    Ok(())
+}
+
 /// Adds a `Response` to a `Responses` object with the given status code, Content-Type and `SchemaObject`.
 pub fn add_schema_response(
     responses: &mut Responses,