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18 | 18 | \providecommand\HyField@AuxAddToCoFields[2]{} |
19 | 19 | \providecommand\BKM@entry[2]{} |
20 | 20 | \BKM@entry{id=1,dest={73656374696F6E2E31},srcline={170}}{5C3337365C3337375C303030495C3030306E5C303030745C303030725C3030306F5C303030645C303030755C303030635C303030745C303030695C3030306F5C3030306E} |
21 | | -\BKM@entry{id=2,dest={73656374696F6E2E32},srcline={181}}{5C3337365C3337375C303030435C3030306F5C303030685C3030306F5C303030725C303030745C3030305C3034305C303030735C303030745C303030615C303030745C303030655C3030302D5C303030745C303030725C303030615C3030306E5C303030735C303030695C303030745C303030695C3030306F5C3030306E5C3030305C3034305C3030306D5C3030306F5C303030645C303030655C3030306C5C303030735C3030305C3034305C3030305C3035305C303030635C303030535C303030545C3030304D5C303030735C3030305C303531} |
22 | 21 | \@writefile{toc}{\contentsline {section}{\numberline {1}Introduction}{2}{section.1}\protected@file@percent } |
23 | 22 | \newlabel{introduction}{{1}{2}{Introduction}{section.1}{}} |
24 | | -\BKM@entry{id=3,dest={73756273656374696F6E2E322E31},srcline={196}}{5C3337365C3337375C303030525C303030615C303030745C303030655C303030735C3030305C3034305C303030765C303030655C303030725C303030735C303030755C303030735C3030305C3034305C303030705C303030725C3030306F5C303030625C303030615C303030625C303030695C3030306C5C303030695C303030745C303030695C303030655C30303073} |
| 23 | +\BKM@entry{id=2,dest={73656374696F6E2E32},srcline={181}}{5C3337365C3337375C303030435C3030306F5C303030685C3030306F5C303030725C303030745C3030305C3034305C303030735C303030745C303030615C303030745C303030655C3030302D5C303030745C303030725C303030615C3030306E5C303030735C303030695C303030745C303030695C3030306F5C3030306E5C3030305C3034305C3030306D5C3030306F5C303030645C303030655C3030306C5C303030735C3030305C3034305C3030305C3035305C303030635C303030535C303030545C3030304D5C303030735C3030305C303531} |
25 | 24 | \@writefile{toc}{\contentsline {section}{\numberline {2}Cohort state-transition models (cSTMs)}{3}{section.2}\protected@file@percent } |
26 | 25 | \newlabel{cohort-state-transition-models-cstms}{{2}{3}{Cohort state-transition models (cSTMs)}{section.2}{}} |
| 26 | +\BKM@entry{id=3,dest={73756273656374696F6E2E322E31},srcline={196}}{5C3337365C3337375C303030525C303030615C303030745C303030655C303030735C3030305C3034305C303030765C303030655C303030725C303030735C303030755C303030735C3030305C3034305C303030705C303030725C3030306F5C303030625C303030615C303030625C303030695C3030306C5C303030695C303030745C303030695C303030655C30303073} |
27 | 27 | \@writefile{toc}{\contentsline {subsection}{\numberline {2.1}Rates versus probabilities}{4}{subsection.2.1}\protected@file@percent } |
28 | 28 | \newlabel{rates-versus-probabilities}{{2.1}{4}{Rates versus probabilities}{subsection.2.1}{}} |
29 | 29 | \newlabel{eq:rate-to-prob-ann}{{1}{4}{Rates versus probabilities}{equation.2.1}{}} |
30 | 30 | \newlabel{eq:prob-to-rate-ann}{{2}{4}{Rates versus probabilities}{equation.2.2}{}} |
31 | 31 | \newlabel{eq:rate-ann-to-month}{{3}{4}{Rates versus probabilities}{equation.2.3}{}} |
32 | | -\newlabel{eq:rate-to-prob-month}{{4}{4}{Rates versus probabilities}{equation.2.4}{}} |
33 | 32 | \BKM@entry{id=4,dest={73656374696F6E2E33},srcline={234}}{5C3337365C3337375C303030545C303030695C3030306D5C303030655C3030302D5C303030695C3030306E5C303030645C303030655C303030705C303030655C3030306E5C303030645C303030655C3030306E5C303030745C3030305C3034305C303030635C303030535C303030545C3030304D5C3030305C3034305C303030645C303030795C3030306E5C303030615C3030306D5C303030695C303030635C30303073} |
| 33 | +\newlabel{eq:rate-to-prob-month}{{4}{5}{Rates versus probabilities}{equation.2.4}{}} |
34 | 34 | \@writefile{toc}{\contentsline {section}{\numberline {3}Time-independent cSTM dynamics}{5}{section.3}\protected@file@percent } |
35 | 35 | \newlabel{time-independent-cstm-dynamics}{{3}{5}{Time-independent cSTM dynamics}{section.3}{}} |
36 | 36 | \gdef \LT@i {\LT@entry |
|
45 | 45 | \newlabel{case-study-sick-sicker-model}{{4}{6}{Case study: Sick-Sicker model}{section.4}{}} |
46 | 46 | \@writefile{lof}{\contentsline {figure}{\numberline {1}{\ignorespaces State-transition diagram of the time-independent Sick-Sicker cohort state-transition model, showing all possible states (labeled with state names) and transitions (labeled with transition probability variable names).}}{6}{figure.1}\protected@file@percent } |
47 | 47 | \newlabel{fig:STD-Sick-Sicker}{{1}{6}{State-transition diagram of the time-independent Sick-Sicker cohort state-transition model, showing all possible states (labeled with state names) and transitions (labeled with transition probability variable names)}{figure.1}{}} |
48 | | -\newlabel{tab:param-table}{{2}{7}{Case study: Sick-Sicker model}{table.2}{}} |
49 | | -\@writefile{lot}{\contentsline {table}{\numberline {2}{ Description of parameters, their R variable name, base-case values and distribution.}}{7}{table.2}\protected@file@percent } |
50 | 48 | \gdef \LT@ii {\LT@entry |
51 | 49 | {1}{201.18843pt}\LT@entry |
52 | 50 | {1}{81.40239pt}\LT@entry |
53 | 51 | {1}{94.4145pt}\LT@entry |
54 | 52 | {1}{92.74968pt}} |
| 53 | +\newlabel{tab:param-table}{{2}{8}{Case study: Sick-Sicker model}{table.2}{}} |
| 54 | +\@writefile{lot}{\contentsline {table}{\numberline {2}{ Description of parameters, their R variable name, base-case values and distribution.}}{8}{table.2}\protected@file@percent } |
55 | 55 | \BKM@entry{id=6,dest={73656374696F6E2E35},srcline={582}}{5C3337365C3337375C303030435C3030306F5C303030735C303030745C3030305C3034305C303030615C3030306E5C303030645C3030305C3034305C303030655C303030665C303030665C303030655C303030635C303030745C303030695C303030765C303030655C3030306E5C303030655C303030735C303030735C3030305C3034305C3030306F5C303030755C303030745C303030635C3030306F5C3030306D5C303030655C30303073} |
56 | 56 | \@writefile{lot}{\contentsline {table}{\numberline {3}{\ignorespaces The distribution of the cohort under strategies SoC and A for the first six cycles of the time-independent Sick-Sicker model. The first row, labeled with cycle 0, contains the distribution of the cohort at time zero.}}{13}{table.3}\protected@file@percent } |
57 | 57 | \newlabel{tab:Trace}{{3}{13}{The distribution of the cohort under strategies SoC and A for the first six cycles of the time-independent Sick-Sicker model. The first row, labeled with cycle 0, contains the distribution of the cohort at time zero}{table.3}{}} |
58 | 58 | \@writefile{lof}{\contentsline {figure}{\numberline {2}{\ignorespaces Cohort trace of the time-independent cSTM under strategies SoC and A.}}{13}{figure.2}\protected@file@percent } |
59 | 59 | \newlabel{fig:Sick-Sicker-Trace-TimeHom}{{2}{13}{Cohort trace of the time-independent cSTM under strategies SoC and A}{figure.2}{}} |
60 | | -\@writefile{toc}{\contentsline {section}{\numberline {5}Cost and effectiveness outcomes}{13}{section.5}\protected@file@percent } |
61 | | -\newlabel{cost-and-effectiveness-outcomes}{{5}{13}{Cost and effectiveness outcomes}{section.5}{}} |
62 | 60 | \BKM@entry{id=7,dest={73756273656374696F6E2E352E31},srcline={587}}{5C3337365C3337375C303030535C303030745C303030615C303030745C303030655C3030305C3034305C303030725C303030655C303030775C303030615C303030725C303030645C30303073} |
| 61 | +\@writefile{toc}{\contentsline {section}{\numberline {5}Cost and effectiveness outcomes}{14}{section.5}\protected@file@percent } |
| 62 | +\newlabel{cost-and-effectiveness-outcomes}{{5}{14}{Cost and effectiveness outcomes}{section.5}{}} |
63 | 63 | \@writefile{toc}{\contentsline {subsection}{\numberline {5.1}State rewards}{14}{subsection.5.1}\protected@file@percent } |
64 | 64 | \newlabel{state-rewards}{{5.1}{14}{State rewards}{subsection.5.1}{}} |
65 | 65 | \newlabel{eq:exp-rew-cycle}{{5}{14}{State rewards}{equation.5.5}{}} |
|
70 | 70 | \@writefile{toc}{\contentsline {subsection}{\numberline {5.3}Discounting future rewards}{16}{subsection.5.3}\protected@file@percent } |
71 | 71 | \newlabel{discounting-future-rewards}{{5.3}{16}{Discounting future rewards}{subsection.5.3}{}} |
72 | 72 | \newlabel{eq:tot-exp-disc-rewd}{{6}{16}{Discounting future rewards}{equation.5.6}{}} |
73 | | -\newlabel{eq:tot-exp-disc-rewd-wcc}{{7}{16}{Discounting future rewards}{equation.5.7}{}} |
74 | 73 | \BKM@entry{id=10,dest={73656374696F6E2E36},srcline={762}}{5C3337365C3337375C303030495C3030306E5C303030635C303030725C303030655C3030306D5C303030655C3030306E5C303030745C303030615C3030306C5C3030305C3034305C303030635C3030306F5C303030735C303030745C3030302D5C303030655C303030665C303030665C303030655C303030635C303030745C303030695C303030765C303030655C3030306E5C303030655C303030735C303030735C3030305C3034305C303030725C303030615C303030745C303030695C3030306F5C303030735C3030305C3034305C3030305C3035305C303030495C303030435C303030455C303030525C303030735C3030305C303531} |
| 74 | +\newlabel{eq:tot-exp-disc-rewd-wcc}{{7}{17}{Discounting future rewards}{equation.5.7}{}} |
75 | 75 | \@writefile{lot}{\contentsline {table}{\numberline {4}{\ignorespaces Total expected discounted QALYs and costs per average individual in the cohort of the Sick-Sicker model by strategy accounting for within-cycle correction.}}{17}{table.4}\protected@file@percent } |
76 | 76 | \newlabel{tab:Expected-outcomes-table}{{4}{17}{Total expected discounted QALYs and costs per average individual in the cohort of the Sick-Sicker model by strategy accounting for within-cycle correction}{table.4}{}} |
77 | 77 | \@writefile{toc}{\contentsline {section}{\numberline {6}Incremental cost-effectiveness ratios (ICERs)}{17}{section.6}\protected@file@percent } |
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