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Extend statistical inference backends #64

@Konrad1991

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@Konrad1991
  • Linear Mixed Models (LMM)
    Support hierarchical and split-plot experimental structures (random intercepts/slopes) and enable simulation from fitted models for power analysis.

  • Randomization / permutation tests
    Provide design-based inference aligned with the randomization engine, including restricted permutations for blocked and stratified designs.
    Anderson2001, Anderson2003, and Enrst2004

  • Bootstrap inference
    Add nonparametric, residual, and parametric bootstrap methods as robust alternatives to classical parametric tests and for simulation-based sample-size estimation. Using boot::boot and/or car::Boot

  • Bayesian models
    Introduce Bayesian linear and hierarchical models with posterior predictive simulation to support adaptive and optimization-driven experimental workflows (maybe using brms)

All methods should integrate with the existing Monte-Carlo simulation framework used for power and sample-size determination.

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