Is it possible that this tool used with other viruses?

[virologist]

Hi, @3BioCompBio

Very interesting tool to analyze viral fitness at the population level.
Is it possible that this tool used with other viruses?

Best,
Yang

[3BioCompBio]

Hi Yang,

Thank you for your interest in SpikePro. This method is dedicated to the study of SARS-CoV-2 even if an analogous pipeline can in principle be constructred for any viruses if the protein structural information are available. Do you have in mind some specific virus?

Best,
Fabrizio

[virologist]

Hi, @3BioCompBio Fabrizio,

Thanks for your reply.
I am interested in the avian influenza virus (e.g. H5, H7). I think many protein structures relative to HA of these subtypes may available in the PDB database. So, any idea to make the pipeline come true?

Best wishes,
Yang

[3BioCompBio]

Hi Yang,

if there are structures then yes, the construction of the pipeline is not so different from SARS-CoV-2 one and we could try to set up it even if at the moment we are a bit busy. We can try to have a more close look to it next month if it is not too urgent. Send me your email at fabriziopucci81 at gmail.com I will keep u update.

Ciao,
Fabrizio